ArticleApplied and environmental microbiology2005
Uptake of CdSe and CdSe/ZnS quantum dots into bacteria via purine-dependent mechanisms.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 239 citations in OpenAlex.
- Contemporary strategies and approaches for characterizing composition and enhancing biofilm penetration targeting bacterial extracellular polymeric substances.Journal of pharmaceutical analysis · 2024Review
- Antibacterial Activity of CdTe/ZnS Quantum Dot-β Lactum Antibiotic Conjugates.Journal of fluorescence · 2024Article
- Nanofertilizer Possibilities for Healthy Soil, Water, and Food in Future: An Overview.Frontiers in plant science · 2022Review
- Aptamer Conjugated Indium Phosphide Quantum Dots with a Zinc Sulphide Shell as Photoluminescent Labels forNanomaterials (Basel, Switzerland) · 2021Article
- Vital roles of sustainable nano-fertilizers in improving plant quality and quantity-an updated review.Saudi journal of biological sciences · 2021Review
- A review on the cytotoxicity of graphene quantum dots: from experiment to simulation.Nanoscale advances · 2021Review
- Toxicity of cadmium selenide nanoparticles on the green microalgaChlorella vulgaris: inducing antioxidative defense response.Environmental science and pollution research international · 2019Article
- The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions.International journal of nanomedicine · 2016Article
- Glyconanomaterials for Combating Bacterial Infections.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015Article
- Selective targeting of Mycobacterium smegmatis with trehalose-functionalized nanoparticles.Chemical communications (Cambridge, England) · 2015Article
- Nanotechnology in dentistry: prevention, diagnosis, and therapy.International journal of nanomedicine · 2015Review
- Article
- The Effect of Natural Organic Matter on Mercury Methylation by Desulfobulbus propionicus 1pr3.Frontiers in microbiology · 2015Article
- Development and use of a quantum dot probe to track multiple yeast strains in mixed culture.Scientific reports · 2014Article
- Chemical basis of interactions between engineered nanoparticles and biological systems.Chemical reviews · 2014Review
- Molecular imaging of bacterial infections in vivo: the discrimination of infection from inflammation.Informatics (MDPI) · 2014Article
- Facile method for the synthesis of silver nanoparticles using 3-hydrazino-isatin derivatives in aqueous methanol and their antibacterial activity.International journal of nanomedicine · 2014Article
- Toxicity and genotoxicity of organic and inorganic nanoparticles to the bacteria Vibrio fischeri and Salmonella typhimurium.Ecotoxicology (London, England) · 2012Article
- Quantum dots: an insight and perspective of their biological interaction and how this relates to their relevance for clinical use.Theranostics · 2012Article
- CdTe and CdSe quantum dots cytotoxicity: a comparative study on microorganisms.Sensors (Basel, Switzerland) · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantum dots (QDs) rendered water soluble for biological applications are usually passivated by several inorganic and/or organic layers in order to increase fluorescence yield. However, these coatings greatly increase the size of the particle, making uptake by microorganisms impossible. We find that adenine- and AMP-conjugated QDs are able to label bacteria only if the particles are <5 nm in diameter. Labeling is dependent upon purine-processing mechanisms, as mutants lacking single enzymes demonstrate a qualitatively different signal than do wild-type strains. This is shown for two example species, one gram negative and one gram positive. Wild-type Bacillus subtilis incubated with QDs conjugated to adenine are strongly fluorescent; very weak signal is seen in mutant cells lacking either adenine deaminase or adenosine phosphoribosyltransferase. Conversely, QD-AMP conjugates label mutant strains more efficiently than the wild type. In Escherichia coli, QD conjugates are taken up most strongly by adenine auxotrophs and are extruded from the cells over a time course of hours. No fluorescent labeling is seen in killed bacteria or in the presence of EDTA or an excess of unlabeled adenine, AMP, or hypoxanthine. Spectroscopy and electron microscopy suggest that QDs of <5 nm can enter the cells whole, probably by means of oxidative damage to the cell membrane which is aided by light.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.