ArticleApplied and environmental microbiology2005
Variation in acid resistance among shiga toxin-producing clones of pathogenic Escherichia coli.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 79 citations in OpenAlex.
- Antibiotic resistance associated lactic acid cross tolerance in Shiga-toxin producingFrontiers in microbiology · 2023Article
- Investigation ofFoods (Basel, Switzerland) · 2021Article
- Article
- Core and Accessory Genome Comparison of Australian and International Strains of O157 Shiga Toxin-ProducingFrontiers in microbiology · 2020Article
- Article
- Regulation ofEcoSal Plus · 2017Review
- Escherichia coli O157:H7 bacteriophage Φ241 isolated from an industrial cucumber fermentation at high acidity and salinity.Frontiers in microbiology · 2015Article
- Vaginal biogenic amines: biomarkers of bacterial vaginosis or precursors to vaginal dysbiosis?Frontiers in physiology · 2015Article
- NsrR, GadE, and GadX interplay in repressing expression of the Escherichia coli O157:H7 LEE pathogenicity island in response to nitric oxide.PLoS pathogens · 2014Article
- Contribution of urease to colonization by Shiga toxin-producing Escherichia coli.Infection and immunity · 2012Article
- Polymorphisms in rpoS and stress tolerance heterogeneity in natural isolates of Cronobacter sakazakii.Applied and environmental microbiology · 2012Article
- The constancy of global regulation across a species: the concentrations of ppGpp and RpoS are strain-specific in Escherichia coli.BMC microbiology · 2011Article
- Survival of Escherichia coli in the environment: fundamental and public health aspects.The ISME journal · 2011Review
- Inactivation of alternative sigma factor 54 (RpoN) leads to increased acid resistance, and alters locus of enterocyte effacement (LEE) expression in Escherichia coli O157 : H7.Microbiology (Reading, England) · 2010Article
- Differential expression of virulence and stress fitness genes between Escherichia coli O157:H7 strains with clinical or bovine-biased genotypes.Applied and environmental microbiology · 2010Article
- Escherichia coli O157:H7 and other E. coli strains share physiological properties associated with intestinal colonization.Applied and environmental microbiology · 2009Article
- Characterization of the Escherichia coli O157:H7 Sakai GadE regulon.Journal of bacteriology · 2009Article
- Growth and Survival of Acid-Resistant and Non-Acid-Resistant Shiga-Toxin-Producing Escherichia coli Strains during the Manufacture and Ripening of Camembert Cheese.International journal of microbiology · 2009Article
- Functional heterogeneity of RpoS in stress tolerance of enterohemorrhagic Escherichia coli strains.Applied and environmental microbiology · 2006Article
- Produce isolates of the Escherichia coli Ont:H52 serotype that carry both Shiga toxin 1 and stable toxin genes.Applied and environmental microbiology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogenic strains of Escherichia coli, such as E. coli O157:H7, have a low infectious dose and an ability to survive in acidic foods. These bacteria have evolved at least three distinct mechanisms of acid resistance (AR), including two amino acid decarboxylase-dependent systems (arginine and glutamate) and a glucose catabolite-repressed system. We quantified the survival rates for each AR mechanism separately in clinical isolates representing three groups of Shiga toxin-producing E. coli (STEC) clones (O157:H7, O26:H11/O111:H8, and O121:H19) and six commensal strains from ECOR group A. Members of the STEC clones were not significantly more acid resistant than the commensal strains when analyzed using any individual AR mechanism. The glutamate system provided the best protection in a highly acidic environment for all groups of isolates (<0.1 log reduction in CFU/ml per hour at pH 2.0). Under these conditions, there was notable variation in survival rates among the 30 O157:H7 strains, which depended in part on Mg(2+) concentration. The arginine system provided better protection at pH 2.5, with a range of 0.03 to 0.41 log reduction per hour, compared to the oxidative system, with a range of 0.13 to 0.64 log reduction per hour. The average survival rate for the O157:H7 clonal group was significantly less than that of the other STEC clones in the glutamate and arginine systems and significantly less than that of the O26/O111 clone in the oxidative system, indicating that this clonal group is not exceptionally acid resistant with these specific mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.