Evidence map›Paper›PMID 1586782›Full record

Trial reportBMJ (Clinical research ed.)1992

Randomised controlled trial of cardioprotective diet in patients with recent acute myocardial infarction: results of one year follow up.

R B Singh, S S Rastogi, R Verma, B Laxmi, R Singh, S Ghosh, M A Niaz

Expression of concernOpen access · bronzeAbstract readClinical TrialRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ (Clinical research ed.), 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 70 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 16 pooled it
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 16 syntheses or guidelines pooled it, 460 citations in OpenAlex.

  1. The effectiveness of the Mediterranean Diet for primary and secondary prevention of cardiovascular disease: An umbrella review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2025
    Pooled it
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  3. Reduction in saturated fat intake for cardiovascular disease.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Effects of total fat intake on body fatness in adults.The Cochrane database of systematic reviews · 2020
    Pooled it
  5. Reduction in saturated fat intake for cardiovascular disease.The Cochrane database of systematic reviews · 2020
    Pooled it
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  10. Effects of total fat intake on body weight.The Cochrane database of systematic reviews · 2015
    Pooled it
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  12. Reduced or modified dietary fat for preventing cardiovascular disease.The Cochrane database of systematic reviews · 2012
    Pooled it
  13. Reduced or modified dietary fat for preventing cardiovascular disease.The Cochrane database of systematic reviews · 2011
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

R B SinghMedical Hospital and Research Centre, Moradabad, India.
S S Rastogi
R Verma
B Laxmi
R Singh
S Ghosh
M A Niaz
Teerthanker Mahaveer Medical College & Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo test whether a fat reduced diet rich in soluble dietary fibre, antioxidant vitamins, and minerals reduces complications and mortality after acute myocardial infarction.

designRandomised, single blind, controlled trial.

settingPrimary and secondary care research centre for patients with myocardial infarction. SUBJECTS: 505 patients with suspected acute myocardial infarction. Those with definite or possible acute myocardial infarction and unstable angina based on World Health Organisation criteria were assigned to diet A (n = 204) or diet B (n = 202) within 24-48 hours of infarction.

interventionsBoth groups were advised to follow a fat reduced diet. Group A was also advised to eat more fruit, vegetables, nuts, and grain products.

main outcome measuresMortality from cardiac disease and other causes. Serum lipid concentrations and compliance with diet.

resultsBlood lipoprotein concentrations and body weight fell significantly in patients in group A compared with those in group B (cholesterol fell by 0.74 mmol/l in group A v 0.32 mmol/l in group B, 95% confidence interval of difference 0.14 to 0.70, and weight by 7.1 v 3.0 kg, 0.52 to 7.68). The incidence of cardiac events was significantly lower in group A than group B (50 v 82 patients, p less than 0.001). Group A also had lower total mortality (21 v 38 died, p less than 0.01) than group B.

conclusionsComprehensive dietary changes in conjunction with weight loss immediately after acute myocardial infarction may modulate blood lipoproteins and significantly reduce complications and mortality after one year.

Indexed as

AdultAgedCardiovascular DiseasesFollow-Up StudiesHumansLipidsLipoproteinsMiddle AgedMyocardial InfarctionSingle-Blind MethodSmokingWeight LossLipidsLipoproteins

Identifiers

PMID1586782
PMCPMC1881705
OpenAlexW2051750844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.