Evidence map›Paper›PMID 15866892›Full record

ArticleThe Journal of cell biology2005

Capacitative calcium entry: sensing the calcium stores.

James W Putney

Abstract readComment
In one paragraph

Article in The Journal of cell biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 267 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Wound Repair and CaCells · 2024
    Review
  6. Physiological functions of calcium signaling via Orai1 in cancer.The journal of physiological sciences : JPS · 2023
    Review
  7. Localisation of Intracellular Signals and Responses during Phagocytosis.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Physiological and Pathological Relevance of Selective and Nonselective CaAdvances in experimental medicine and biology · 2021
    Article
  15. Review
  16. STIM Proteins: An Ever-Expanding Family.International journal of molecular sciences · 2020
    Review
  17. Review
  18. Prostaglandin ECancer science · 2020
    Article
  19. Article
  20. Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James W PutneyLaboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health Department of Health and Human Services, Research Triangle Park, NC 27709, USA. putney@niehs.nih.gov
National Institute of Environmental Health Sciences · US

Funding

Capacitative Calcium EntryZIAES090087 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BIRD, GARY · 2009 to 2019
$22.0M
CAPACITATIVE CALCIUM ENTRYZ01ES090087 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PUTNEY, JAMES W · 1997 to 2008
$5.2M
6 · The paper itself

Abstract

A long-standing mystery in the cell biology of calcium channel regulation is the nature of the signal linking intracellular calcium stores to plasma membrane capacitative calcium entry channels. An RNAi-based screen of selected Drosophila genes has revealed that a calcium-binding protein, stromal interaction molecule (STIM), plays an essential role in the activation of these channels and may be the long sought sensor of calcium store content.

Indexed as

Calcium-Binding ProteinsCalcium ChannelsCalcium SignalingCell MembraneDrosophila ProteinsAnimalsHumansMembrane ProteinsNeoplasm ProteinsProtein Structure, TertiaryStromal Interaction Molecule 1Calcium-Binding ProteinsCalcium ChannelsDrosophila ProteinsMembrane ProteinsNeoplasm ProteinsSTIM1 protein, humanStromal Interaction Molecule 1

Identifiers

PMID15866892
PMCPMC2171919
OpenAlexW2065638011

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.