ReviewMarine biotechnology (New York, N.Y.)
Fishing for answers with transposons.
Review in Marine biotechnology (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Clinical applications of gamma delta T cells with multivalent immunity.Frontiers in immunology · 2014Review
- A hyperactive sleeping beauty transposase enhances transgenesis in zebrafish embryos.BMC research notes · 2010Article
- Transposons as tools for enhancer trap screens in vertebrates.Genome biology · 2007Review
- Meganuclease and transposon mediated transgenesis in medaka.Genome biology · 2007Review
- Insertional mutagenesis strategies in zebrafish.Genome biology · 2007Review
- Pluripotency and chimera competence of an embryonic stem cell line from the sea perch (Lateolabrax japonicus).Marine biotechnology (New York, N.Y.)Article
- Site-directed gene integration in transgenic zebrafish mediated by cre recombinase using a combination of mutant lox sites.Marine biotechnology (New York, N.Y.)Article
- Efficient transfection strategy for the spatiotemporal control of gene expression in zebrafish.Marine biotechnology (New York, N.Y.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transposons are one means that nature has used to introduce new genetic material into chromosomes of organisms from every kingdom. They have been extensively used in prokaryotic and lower eukaryotic systems, but until recently there was no transposon that had significant activity in vertebrates. The Sleeping Beauty (SB) transposon system was developed to direct the integration of precise DNA sequences into chromosomes. The SB system was derived from salmonid sequences that had been inactive for more than 10 million years. SB transposons have been used for two principle uses--as a vector for transgenesis and as a method for introducing various trap vectors into (gene-trap) or in the neighborhood of (enhancer-trap) genes to identify their functions. Results of these studies show that SB-mediated transgenesis is more efficient than that by injection of simple plasmids and that expression of transgenesis is stable and reliable following passage through the germline.
Indexed as
Identifiers
15864468What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.