ArticleNature genetics2005
Epigenetic status of human embryonic stem cells.
Article in Nature genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
62 citing papers in PubMed.
- Culture-dependent decoupling ofEpigenetics · 2026Article
- Epigenetic Deregulation of Transposable Elements Links Developmental Processes and Tumorigenesis.International journal of molecular sciences · 2026Review
- Mesoderm and myogenesis-related lncRNAs as Potential Markers of Myogenic Differentiation of Control and miR145 or miR181 Stimulated Mouse Pluripotent Stem Cells.Stem cell reviews and reports · 2026Article
- CRISPR-Cas9-induced double-strand breaks disrupt maintenance of epigenetic information.Genome biology · 2025Article
- Why are imprints unstable in pluripotent stem cells?Biochemical Society transactions · 2025Article
- BrewerIX enables allelic expression analysis of imprinted and X-linked genes from bulk and single-cell transcriptomes.Communications biology · 2022Article
- Why stem/progenitor cells lose their regenerative potential.World journal of stem cells · 2021Review
- Large-scale analysis of imprinting in naive human pluripotent stem cells reveals recurrent aberrations and a potential link to FGF signaling.Stem cell reports · 2021Article
- Identification of an epigenetic signature in human induced pluripotent stem cells using a linear machine learning model.Human cell · 2021Article
- Generation of human androgenetic induced pluripotent stem cells.Scientific reports · 2020Article
- The application of cell surface markers to demarcate distinct human pluripotent states.Experimental cell research · 2020Review
- Epigenetic aberrations in human pluripotent stem cells.The EMBO journal · 2019Review
- How Does Reprogramming to Pluripotency Affect Genomic Imprinting?Frontiers in cell and developmental biology · 2019Review
- Analysis of the Paternally-Imprinted DLK1-MEG3 and IGF2-H19 Tandem Gene Loci in NT2 Embryonal Carcinoma Cells Identifies DLK1 as a Potential Therapeutic Target.Stem cell reviews and reports · 2018Article
- Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors.Regenerative therapy · 2018Article
- Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells.Science (New York, N.Y.) · 2017Article
- A G-quadruplex structure at the 5' end of the H19 coding region regulates H19 transcription.Scientific reports · 2017Article
- Human Long Noncoding RNA Regulation of Stem Cell Potency and Differentiation.Stem cells international · 2017Review
- Stem cells: Aspiring to naivety.Nature · 2016Article
- White paper on guidelines concerning enteric nervous system stem cell therapy for enteric neuropathies.Developmental biology · 2016Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We examined the allele-specific expression of six imprinted genes and the methylation profiles of three imprinting control regions to assess the epigenetic status of human embryonic stem cells. We identified generally monoallelic gene expression and normal methylation patterns. During prolonged passage, one cell line became biallelic with respect to H19, but without loss of the gametic methylation imprint. These data argue for a substantial degree of epigenetic stability in human embryonic stem cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.