Evidence map›Paper›PMID 15863801›Full record

ArticleThe American journal of psychiatry2005

Relief of expressed suicidal intent by ECT: a consortium for research in ECT study.

Charles H Kellner, Max Fink, Rebecca Knapp, Georgios Petrides, Mustafa Husain, Teresa Rummans, Martina Mueller, Hilary Bernstein, Keith Rasmussen, Kevin O'connor and 6 more

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in The American journal of psychiatry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06529029 (Efficacy of Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy in Remission of Suicidal Ideation), which is not on this map. Cited by 98 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 9 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06529029 phase2 / phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy of Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive Therapy in Remission of Suicidal Ideation

TypeinterventionalSponsorMichigan State UniversityRan2024 to 2026Enrolled30ConditionsSuicidal Ideation, Major Depressive Disorder, Schizo Affective Disorder, Bipolar DisorderArmsSigma-Stim, RUL LAP-ST (Low-Amplitude Pulse Seizure Therapy - Right Unilateral)
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 9 syntheses or guidelines pooled it, 341 citations in OpenAlex.

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  11. Longitudinal Neurocognitive Effects of Combined Electroconvulsive Therapy (ECT) and Pharmacotherapy in Major Depressive Disorder in Older Adults: Phase 2 of the PRIDE Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Charles H KellnerUniversity of Medicine and Dentistry of New Jersey-New Jersey Medical School, 183 South Orange Ave., F1436, Newark, NJ 07103, USA. kellner@umdnj.edu
Max Fink
Rebecca Knapp
Georgios Petrides
Mustafa Husain
Teresa Rummans
Martina Mueller
Hilary Bernstein
Keith Rasmussen
Kevin O'connor
Glenn Smith
A John Rush
Melanie Biggs
Shawn McClintock
Samuel Bailine
Chitra Malur
Rutgers New Jersey Medical School

Funding

1/8-Prolonging Remission in Depressed Elderly (PRIDE)U01MH055495 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KELLNER, CHARLES H · 2009 to 2013
$2.0M
Continuation ECT vs Pharmacotherapy: Efficacy and SafetyR01MH055495 · NIMH · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KELLNER, CHARLES H · 2002 to 2003
$819k
CONTINUATION ECT VS PHARMACOTHERAPY--EFFICACY AND SAFETYR10MH055495 · NIMH · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KELLNER, CHARLES H · 1997 to 2001
$709k
CONTINUATION ECT VS PHARMACOTHERAPY--EFFICACY AND SAFETYR01MH055486 · NIMH · LONG ISLAND JEWISH MEDICAL CENTER · PI PETRIDES, GEORGIOS · 2002 to 2003
$661k
Continuation ECT versus PharmacotherapyR01MH055489 · NIMH · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI HUSAIN, MUSTAFA M. · 2002 to 2003
$651k
CONTINUATION ECT VS PHARMACOTHERAPHY--SAFETY &EFFICACYR10MH055489 · NIMH · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI HUSAIN, MUSTAFA M. · 1997 to 2001
$636k
Continuation ECT vs Pharmacotherapy: Efficacy &SafetyR01MH055484 · NIMH · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI RUMMANS, TERESA A · 2002 to 2003
$553k
CONTINUATION ECT VS PHARMACOTHERAPY--EFFICACY AND SAFETYR10MH055486 · NIMH · LONG ISLAND JEWISH MEDICAL CENTER · PI PETRIDES, GEORGIOS · 1997 to 2001
$548k
CONTINUATION ECT VS PHARMACOTHERAPY--EFFICACY AND SAFETYR10MH055484 · NIMH · MAYO CLINIC COLL OF MEDICINE, ROCHESTER · PI RUMMANS, TERESA A · 1997 to 2001
$540k
NIMH NIH HHS MH-55484NIMH NIH HHS MH-55485NIMH NIH HHS MH-55486NIMH NIH HHS MH-55489NIMH NIH HHS MH-55495NIMH NIH HHS R01 MH055484NIMH NIH HHS R01 MH055486NIMH NIH HHS R01 MH055489NIMH NIH HHS R01 MH055495NIMH NIH HHS R10 MH055484NIMH NIH HHS R10 MH055486NIMH NIH HHS R10 MH055489NIMH NIH HHS R10 MH055495NIMH NIH HHS U01 MH055495
6 · The paper itself

Abstract

objectiveThis study assessed the incidence, severity, and course of expressed suicidal intent in depressed patients who were treated with ECT. The data are from the first phase of an ongoing, collaborative multicenter study, the overall aim of which was to compare continuation ECT with pharmacotherapy in the prevention of relapse after a successful course of ECT.

methodSuicidal intent, as expressed by patients during an interview, was scored at baseline and before each ECT session with item 3 on the 24-item Hamilton Depression Rating Scale in 444 patients with unipolar depression.

resultsOne hundred thirty-one patients (29.5%) reported suicidal thoughts and acts (score of 3 or 4) at baseline. Scores decreased to 0 after 1 week (three ECT sessions) in 38.2% of the patients, after 2 weeks (six ECT sessions) in 61.1%, and in 80.9% at the end of the course of treatment.

conclusionsExpressed suicidal intent in depressed patients was rapidly relieved with ECT. Evidence-based treatment algorithms for major depressive mood disorders should include dichotomization according to suicide risk, as assessed by interview. For patients at risk, ECT should be considered earlier than at its conventional "last resort" position.

Indexed as

Electroconvulsive TherapySuicide PreventionAdultCombined Modality TherapyDepressive DisorderFemaleHumansIncidenceLithiumMaleMiddle AgedNortriptylinePsychiatric Status Rating ScalesRisk FactorsSuicideTreatment OutcomeLithiumNortriptyline

Identifiers

PMID15863801
PMCPMC3684568
OpenAlexW2140658729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.