ReviewJournal of perinatology : official journal of the California Perinatal Association2005
Amniotic fluid: not just fetal urine anymore.
Review in Journal of perinatology : official journal of the California Perinatal Association, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04886960 (A Phase I/II Randomized Double-Blinded Standard of Care), which is not on this map. Cited by 271 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Phase I/II Randomized Double-Blinded Standard of Care (Corticosteroid) vs. Sterile Amniotic Fluid for Osteoarthritis
Who cites it
271 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evaluation of Fetal Exposures to Metals and Metalloids through Meconium Analyses: A Review.International journal of environmental research and public health · 2021Pooled it
- Routine oro/nasopharyngeal suction versus no suction at birth.The Cochrane database of systematic reviews · 2017Pooled it
- The safety and effectiveness of lumbar transforaminal injection of sterile amniotic fluid filtrate compared to steroid for lumbosacral radicular pain due to spinal stenosis: a phase I/II double-blinded randomized trial.Pain medicine (Malden, Mass.) · 2026Trial
- A randomized, double-blinded, placebo-controlled clinical trial of sterile filtered human amniotic fluid for treatment of COVID-19.BMC infectious diseases · 2023Trial
- Oropharyngeal administration of colostrum for preventing necrotizing enterocolitis and late-onset sepsis in preterm infants with gestational age ≤ 32 weeks: a pilot single-center randomized controlled trial.International breastfeeding journal · 2021Trial
- The amniotic fluid cell-free transcriptome in spontaneous preterm labor.Scientific reports · 2021Trial
- Amniotic fluid cell-free transcriptome: a glimpse into fetal development and placental cellular dynamics during normal pregnancy.BMC medical genomics · 2020Trial
- Esophageal peristalsis in health and disease: mechanistic insights.Physiological reviews · 2026Review
- Prenatal consequences of GALT deficiency in a rat model of classic galactosemia.PLoS genetics · 2026Article
- Coalescing nephron and ureteric bud progenitors potentiates nephrogenesis in recellularized kidney scaffolds.bioRxiv : the preprint server for biology · 2026Article
- The prenatal sex steroid theory of autism after 25 years.Nature human behaviour · 2026Review
- Normative range for MRI amniotic fluid volume from 16 to 36 gestational weeks: Absolute and relative values, and correlation to ultrasound.Acta obstetricia et gynecologica Scandinavica · 2026Observational
- Application of non-targeted analysis for the identification of novel environmental contaminants in amniotic fluid.Journal of exposure science & environmental epidemiology · 2026Article
- Perinatal outcomes of twin pregnancies complicated by early twin-to-twin transfusion syndrome treated with fetoscopic laser surgery.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2026Article
- Utility of a physiologically-based pharmacokinetic model for investigating time-dependent variability in the fetal-to-maternal plasma concentration ratio of digoxin.Journal of pharmacokinetics and pharmacodynamics · 2026Article
- Body Water During Pregnancy: Physiology, Clinical Significance and Assessment Methods: A Narrative Review.Nutrients · 2026Review
- Development of an Artificial Intelligence-Based Chromosome Interpretation System for Amniotic Fluid Karyotyping.International journal of molecular sciences · 2026Article
- Maternal Sucrose Intake during Pregnancy Alone Disrupts Testosterone and Allopregnanolone Levels in the Fetal Brain of Rats.The Journal of nutrition · 2026Article
- The Wnt/β-catenin pathway maintains homeostasis of amniocytes in Down syndrome.BMC molecular and cell biology · 2026Article
- Rapid clearance of bacteria from maternal bloodstream after delivery in pregnancies complicated by preterm pre-labor rupture of the membranes.Scientific reports · 2026Article
211 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amniotic fluid (AF) is a complex substance essential to fetal well-being. This article reviews recent discoveries and the current understanding of the origin and circulation of AF and its nutritive, protective, and diagnostic functions. Future directions for AF research are also discussed.
Indexed as
Identifiers
15861199What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.