ArticleJournal of clinical pathology2005
A study to determine plasma antioxidant concentrations in patients with Barrett's oesophagus.
Article in Journal of clinical pathology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress.Molecular carcinogenesis · 2016Article
- Dietary intake of vegetables, folate, and antioxidants and the risk of Barrett's esophagus.Cancer causes & control : CCC · 2013Article
- An in vitro co-culture model of esophageal cells identifies ascorbic acid as a modulator of cell competition.BMC cancer · 2011Article
- Dietary antioxidants, fruits, and vegetables and the risk of Barrett's esophagus.The American journal of gastroenterology · 2008Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDietary questionnaire studies have suggested that patients with oesophageal adenocarcinoma are deficient in antioxidants. It is not known whether the same holds true for patients with the precursor lesion, Barrett's oesophagus.
aimsTo evaluate the hypothesis that patients with Barrett's oesophagus are deficient in antioxidants compared with patients without evidence of Barrett's oesophagus. PATIENTS AND
methodsPlasma antioxidant profiles (copper, selenium, zinc; vitamins A, C, and E; carotenoids) were determined for patients with Barrett's oesophagus (n = 36), patients with erosive oesophagitis (n = 32), and patient controls (n = 35).
resultsPatients with Barrett's oesophagus had significantly lower plasma concentrations of selenium, vitamin C, beta cryptoxanthine, and xanthophyll compared with the other groups.
conclusionsThis study confirms the hypothesis that patients with Barrett's oesophagus are deficient in certain antioxidants.
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Registered trials
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