ArticlePediatric nephrology (Berlin, Germany)2005
Association of vitamin-D and calcitonin receptor gene polymorphism in paediatric nephrolithiasis.
Article in Pediatric nephrology (Berlin, Germany), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Association of vitamin D receptor gene polymorphisms and risk of urolithiasis: results of a genetic epidemiology study and comprehensive meta-analysis.Urolithiasis · 2020Pooled it
- Vitamin D receptor gene polymorphisms and susceptibility to urolithiasis: a meta-regression and meta-analysis.BMC nephrology · 2020Pooled it
- Relationship Between theFrontiers in genetics · 2020Pooled it
- Vitamin D receptor gene (VDR) polymorphisms and the urolithiasis risk: an updated meta-analysis based on 20 case-control studies.Urolithiasis · 2014Pooled it
- Effects of vitamin D receptor polymorphisms on urolithiasis risk: a meta-analysis.BMC medical genetics · 2013Pooled it
- Association between calcitonin receptor gene polymorphisms and calcium stone urolithiasis: A meta-analysis.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions.Urolithiasis · 2022Article
- Associations betweenAsian journal of urology · 2022Article
- Genetics of kidney stone disease.Nature reviews. Urology · 2020Review
- Association of TRPV5 gene polymorphism with calcium urolithiasis: a case-control study from West Bengal, India.World journal of urology · 2020Article
- Association between vitamin D receptor gene polymorphisms and idiopathic hypocitraturia in a Chinese Bai population.Urolithiasis · 2019Article
- Metabolic abnormalities and polymorphisms of the vitamin D receptor (VDR) and ZNF365 genes in children with urolithiasis.Urolithiasis · 2014Article
- Vitamin D receptor and type 2 diabetes mellitus: Growing therapeutic opportunities.Indian journal of human genetics · 2012Article
- Association of vitamin D receptor gene polymorphism and calcium urolithiasis in the Chinese Han population.Urological research · 2012Article
- Coding region analysis of vitamin D receptor gene and its association with active calcium stone disease.Urological research · 2012Article
- E-cadherin gene 3'-UTR C/T polymorphism in Turkish patients with nephrolithiasis.Molecular biology reports · 2011Article
- Application of a new method for GWAS in a related case/control sample with known pedigree structure: identification of new loci for nephrolithiasis.PLoS genetics · 2011Article
- Polymorphisms in the vitamin D receptor and the androgen receptor gene associated with the risk of urolithiasis.Indian journal of clinical biochemistry : IJCB · 2010Article
- Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients.Croatian medical journal · 2010Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the role of vitamin-D receptor gene (VDR) and calcitonin receptor (CTR) gene polymorphism in childhood nephrolithiasis in the north Indian population. A control group of 60 healthy paediatric individuals (age range 4-16 years) and 50 paediatric patients (age range 2-14 years) with kidney stones were examined. Polymorphism in both genes (VDR and CTR) was detected by using PCR-based restriction analysis. There was a statistically significant difference between the two groups for the genotypes of the VDR gene Fok-I polymorphism (P =0.007) and the CTR gene (P =0.048) polymorphism. The odds ratio (95% Confidence Interval) for the C allele in those at risk of stone disease was 1.83 (0.82-4.09) in VDR gene polymorphism and 1.99 (0.90-4.39) in the case of CTR gene polymorphism. Our results suggest that the effects of VDR (Fok-I) and CTR gene polymorphism contribute to the understanding of the pathogenesis of urinary calculi. It is also suggestive of a potential candidate gene in the search for genetic causes of paediatric calcium oxalate nephrolithiasis.
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