Evidence map›Paper›PMID 15855180›Full record

ArticleArchives of disease in childhood2005

How accurate is the diagnosis of exercise induced asthma among Vancouver schoolchildren?

M Seear, D Wensley, N West

Open access · bronzeAbstract read
In one paragraph

Article in Archives of disease in childhood, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 147 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Chronic pulmonary embolism in a young athletic woman.Proceedings (Baylor University. Medical Center) · 2015
    Article
  11. Article
  12. Dyspneic athlete.Current reviews in musculoskeletal medicine · 2014
    Article
  13. Article
  14. Review
  15. Exercise-induced laryngeal obstructions: prevalence and symptoms in the general public.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2011
    Article
  16. Management of severe asthma in children.Lancet (London, England) · 2010
    Review
  17. Article
  18. Imitators of exercise-induced bronchoconstriction.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2009
    Article
  19. Exercise-induced bronchospasm in children.Clinical reviews in allergy & immunology · 2008
    Review
  20. Surgical treatment of exercise-induced laryngeal dysfunction.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2007
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

M SeearDepartment of Respiratory Medicine, Children's & Women's Health Centre of British Columbia, Vancouver, British Columbia, Canada. mseear@cw.bc.ca
D Wensley
N West
Children's & Women's Health Centre of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLimited access to exercise testing facilities means that the diagnosis of exercise induced asthma (EIA) is mainly based on self-reported respiratory symptoms. This is open to error since the correlation between exercise related symptoms and subsequent exercise testing has been shown to be poor.

aimTo study the accuracy of clinically diagnosed EIA among Vancouver schoolchildren.

methodsFifty two children referred for investigation of poorly controlled EIA were studied. Following a careful history and physical examination, children performed pulmonary function tests before, then 5 and 15 minutes after a standardised treadmill exercise test. Based on overall assessment, a diagnostic explanation for each child's respiratory complaints was provided as far as possible.

resultsOnly eight children (15.4%) fulfilled diagnostic criteria for EIA (fall in FEV(1) > or =10%). Of the remainder: 12 (23.1%) were unfit, 14 (26.9%) had vocal cord dysfunction/sigh dyspnoea, 7 (13.5%) had a habit cough, and 11 (21.1%) had no abnormalities on clinical or laboratory testing, so were given no diagnosis. Initial reported symptoms of wheeze or cough often changed significantly following a careful history, particularly among the eight elite athletes. The final complaint was sometimes not respiratory, and, in a few cases, was not even associated with exercise.

conclusionsThe clinical diagnosis of EIA is inaccurate among Vancouver schoolchildren, principally due to the unreliability of their initial exercise related complaints. Symptom exaggeration, familiarity with medical jargon, and psychogenic complaints are all common. A careful history is essential in this population before basing any diagnosis on self-reported respiratory symptoms.

Indexed as

AdolescentAsthma, Exercise-InducedChildCoughDiagnosis, DifferentialDyspneaExercise TestFemaleForced Expiratory VolumeHumansLaryngeal DiseasesMaleProspective StudiesRespiratory Function TestsVocal Cords

Identifiers

PMID15855180
PMCPMC1720580
OpenAlexW2069395926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.