ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2005
Outcomes in octogenarians undergoing coronary artery bypass grafting.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- The Predictive Ability of MAGGIC Score After Coronary Artery Bypass Grafting: A Comparative Study.Brazilian journal of cardiovascular surgery · 2023Pooled it
- Article
- Short and long-term outcomes of patients with coronary artery bypass surgery.ARYA atherosclerosis · 2021Article
- Influence of Frailty on Outcome in Older Patients Undergoing Non-Cardiac Surgery - A Systematic Review and Meta-Analysis.Aging and disease · 2020Review
- Epiaortic Ultrasound for Assessment of Intraluminal Atheroma; Insights from the REGROUP Trial.Journal of cardiothoracic and vascular anesthesia · 2020Article
- Predicting operative mortality in octogenarians for isolated coronary artery bypass grafting surgery: a retrospective study.BMC cardiovascular disorders · 2017Article
- New challenges of geriatric cardiology: from clinical to preclinical research.Journal of geriatric cardiology : JGC · 2017Article
- Off-pump coronary artery bypass grafting in octogenarians.Journal of thoracic disease · 2016Review
- Longevity and admission to nursing home according to age after isolated coronary artery bypass surgery: a nationwide cohort study.Interactive cardiovascular and thoracic surgery · 2016Article
- The evolution of cardiovascular surgery in elderly patient: a review of current options and outcomes.BioMed research international · 2014Review
- Coronary artery surgery in octogenarians: evolving strategies for the improvement in early and late results.Heart and vessels · 2012Article
- The clinical value of single photon emission computed tomography myocardial perfusion imaging in cardiac risk stratification of very elderly patients (≥80 years) with suspected coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2012Article
- Outcomes and cost of cardiac surgery in octogenarians is related to type of operation: a multiinstitutional analysis.The Annals of thoracic surgery · 2011Article
- Cardiac surgery in the elderly patient.Deutsches Arzteblatt international · 2009Review
- [Not Available].The open cardiovascular medicine journal · 2009Article
- Decreasing mortality for coronary artery bypass surgery in octogenarians.The Canadian journal of cardiology · 2009Article
- A prototypical Sigma-1 receptor antagonist protects against brain ischemia.Brain research · 2007Article
- Early outcomes of coronary artery bypass with and without cardiopulmonary bypass in octogenarians.The Canadian journal of cardiology · 2006Article
- Coronary interventions in the elderly.Heart (British Cardiac Society) · 2006Review
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough octogenarians are being referred for coronary artery bypass grafting (CABG) with increasing frequency, contemporary outcomes have not been well described. We examined data from 4 Canadian centres to determine outcomes of CABG in this age group.
methodsData for the years 1996 to 2001 were examined in a comparison of octogenarians with patients less than 80 years of age. Logistic regression analysis was used to adjust for preoperative factors and to generate adjusted rates of mortality and postoperative stroke.
resultsA total of 15,070 consecutive patients underwent isolated CABG during the study period. Overall, 725 (4.8%) were 80 years of age or older, the proportion increasing from 3.8% in 1996 to 6.2% in 2001 (p for linear trend = 0.03). The crude rate of death was higher among the octogenarians (9.2% v. 3.8%; p < 0.001), as was the rate of stroke (4.7% v. 1.6%, p < 0.001). The octogenarians had a significantly greater burden of comorbid conditions and more urgent presentation at surgery. After adjustment, the octogenarians remained at greater risk for in-hospital death (odds ratio [OR] 2.64, 95% confidence interval [CI] 1.95-3.57) and stroke (OR 3.25, 95% CI 2.15-4.93). Mortality declined over time for both age groups (p for linear trend < 0.001 for both groups), but the incidence of postoperative stroke did not change (p for linear trend = 0.61 [age < 80 years] and 0.08 [age > or = 80 years]). Octogenarians who underwent elective surgery had crude and adjusted rates of death (OR 1.31, 95% CI 0.60-2.90) and stroke (OR 1.59, 95% CI 0.57-4.44) that were higher than but not significantly different from those for non-octogenarians who underwent elective surgery.
interpretationIn this study, rates of death and stroke were higher among octogenarians, although the adjusted differences in mortality over time were decreasing. The rate of adverse outcomes in association with elective surgery was similar for older and younger patients.
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