ArticleBiophysical journal2005
Inferring the diameter of a biopolymer from its stretching response.
Article in Biophysical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Stacking correlation length in single-stranded DNA.Nucleic acids research · 2024Article
- Compactness of viral genomes: effect of disperse and localized random mutations.Journal of physics. Condensed matter : an Institute of Physics journal · 2018Article
- Article
- Elastic properties and secondary structure formation of single-stranded DNA at monovalent and divalent salt conditions.Nucleic acids research · 2014Article
- On the origin of the unusual behavior in the stretching of single-stranded DNA.The Journal of chemical physics · 2012Article
- Speed limit of protein folding evidenced in secondary structure dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Theory of Biopolymer Stretching at High Forces.Macromolecules · 2010Article
- Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Exploring writhe in supercoiled minicircle DNA.Journal of physics. Condensed matter : an Institute of Physics journal · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigate the stretching response of a thick polymer model by means of extensive stochastic simulations. The computational results are synthesized in an analytic expression that characterizes how the force versus elongation curve depends on the polymer structural parameters: its thickness and granularity (spacing of the monomers). The expression is used to analyze experimental data for the stretching of various different types of biopolymers: polypeptides, polysaccharides, and nucleic acids. Besides recovering elastic parameters (such as the persistence length) that are consistent with those obtained from standard entropic models, the approach allows us to extract viable estimates for the polymers diameter and granularity. This shows that the basic structural polymer features have such a profound impact on the elastic behavior that they can be recovered with the sole input of stretching measurements.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.