SynthesisIntensive care medicine2005
Are somatosensory evoked potentials the best predictor of outcome after severe brain injury? A systematic review.
Synthesis in Intensive care medicine, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.Brain imaging and behavior · 2021Pooled it
- Prognostic value of somatosensory evoked potentials in comatose children: a systematic literature review.Intensive care medicine · 2010Pooled it
- Modulation of Corticospinal Excitability during Action Observation in Patients with Disorders of Consciousness.Brain sciences · 2024Article
- Electrophysiological monitoring of neurological functions at the acute phase of brain injury: An overview of current knowledge and future perspectives in the adult population.European journal of anaesthesiology and intensive care · 2024Review
- Long-term outcomes of post-cardiac arrest patients with severe neurological and functional impairments at hospital discharge.Resuscitation · 2022Article
- Quantifying epileptogenesis in rats with spontaneous and responsive brain state dynamics.Brain communications · 2020Article
- Somatosensory evoked potentials after decompressive craniectomy for traumatic brain injury.Journal of clinical monitoring and computing · 2018Article
- Brainstem Monitoring in the Neurocritical Care Unit: A Rationale for Real-Time, Automated Neurophysiological Monitoring.Neurocritical care · 2017Review
- Real-Time Detection and Monitoring of Acute Brain Injury Utilizing Evoked Electroencephalographic Potentials.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2016Article
- Whole-scalp EEG mapping of somatosensory evoked potentials in macaque monkeys.Brain structure & function · 2015Article
- Phase synchronization in electroencephalographic recordings prognosticates outcome in paediatric coma.PloS one · 2014Article
- Prognosis in prolonged coma patients with diffuse axonal injury assessed by somatosensory evoked potentia.Neural regeneration research · 2013Article
- Does stimulus rate matter when performing somatosensory evoked potentials for coma patients?Neurocritical care · 2010Article
- The self-fulfilling prophecy in intensive care.Theoretical medicine and bioethics · 2009Article
- A combined clinical and MRI approach for outcome assessment of traumatic head injured comatose patients.Journal of neurology · 2008Article
- Malarial retinopathy: a newly established diagnostic sign in severe malaria.The American journal of tropical medicine and hygiene · 2006Review
- Brain dysfunction in critically ill patients--the intensive care unit and beyond.Critical care (London, England) · 2006Review
- Are somatosensory evoked potentials the best predictor of outcome after severe brain injury? Caution in interpreting a systematic review.Intensive care medicine · 2005Article
- A prospective study of outcome predictors after severe brain injury in children.Intensive care medicine · 2005Article
- The role of early electroclinical assessment in improving the evaluation of patients with disorders of consciousness.Functional neurologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMany tests have been used to predict outcome following severe brain injury. We compared predictive powers of clinical examination (pupillary responses, motor responses and Glasgow Coma Scale, GCS), electroencephalography (EEG) and computed tomography (CT) to that of somatosensory evoked potentials (SEPs) in a systematic review. MATERIALS AND
methodsMedline (1976-2002) and Embase (1980-2002) were searched, manual review of article reference lists was conducted, and authors were contacted. We selected 25 studies addressing the prediction of outcome after severe brain injury using SEPs and either GCS, EEG, CT, pupillary or motor responses. Outcomes were determined for patients with normal or bilaterally absent SEPs and graded measures of GCS, EEG, CT, pupillary responses or motor responses. For favourable outcome prediction SEPs were superior in sensitivity, specificity and positive and negative predictive values, except for pupillary responses which had superior sensitivity and GCS which had higher specificity. SEPs had superior summary receiver operating characteristic curves, with the exception of motor responses, and superior ratio of odds ratios. For unfavourable outcome prediction SEPs were superior to the other tests in sensitivity, specificity and positive and negative predictive values, except for motor and pupillary responses, GCS and CTs which had superior sensitivity. All SEP summary receiver operating characteristic curves and pooled ratio of odds ratios were superior.
conclusionsAlthough imperfect, SEPs appear to be the best single overall predictor of outcome. There is sufficient evidence for clinicians to use SEPs in the prediction of outcome after brain injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.