Evidence map›Paper›PMID 15845526›Full record

ArticleInfection and immunity2005

Tumor necrosis factor alpha plays a role in the acceleration of atherosclerosis by Chlamydia pneumoniae in mice.

Lee Ann Campbell, Tadayoshi Nosaka, Michael E Rosenfeld, Kambiz Yaraei, Cho-Chou Kuo

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Animals : an open access journal from MDPI · 2020
    Article
  2. Article
  3. Forum on immunopathological diseases and therapeutics · 2016
    Article
  4. Article
  5. Infection and Atherosclerosis Development.Archives of medical research · 2015
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Immunopathogenesis of Chlamydial Infections.Current topics in microbiology and immunology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lee Ann CampbellDepartment of Pathobiology, Box 357238, University of Washington, Seattle, WA 98195, USA.
Tadayoshi Nosaka
Michael E Rosenfeld
Kambiz Yaraei
Cho-Chou Kuo
University of Washington · US

Funding

ROLE OF CHLAMYDIA PNEUMONIAE INFECTION IN ATHEROGENESISR01HL056036 · NHLBI · UNIVERSITY OF WASHINGTON · PI KUO, CHO-CHOU · 1997 to 2007
$3.2M
NHLBI NIH HHS HL-56036NHLBI NIH HHS R01 HL056036
6 · The paper itself

Abstract

The role of tumor necrosis factor alpha (TNF-alpha) in Chlamydia pneumoniae atherogenesis was evaluated in TNF-alpha p55 receptor-deficient C57BL/6J mice fed a high-fat/high-cholesterol diet. No acceleration of atherosclerotic lesion development was observed in infected mice compared to uninfected mice, indicating that TNF-alpha plays a role in the acceleration of atherosclerosis by C. pneumoniae.

Indexed as

AnimalsArteriosclerosisChlamydophila InfectionsChlamydophila pneumoniaeHyperlipidemiasMaleMiceMice, Inbred C57BLMice, KnockoutReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type ITumor Necrosis Factor-alphaTumor Necrosis Factor Decoy ReceptorsReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type Irecombinant human tumor necrosis factor-binding protein-1Tumor Necrosis Factor-alphaTumor Necrosis Factor Decoy Receptors

Identifiers

PMID15845526
PMCPMC1087380
OpenAlexW2171443322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.