Evidence map›Paper›PMID 15842953›Full record

ReviewCurrent allergy and asthma reports2005

Nasal cytokines as mediators of illness during the common cold.

William J Doyle, David P Skoner, Deborah Gentile

Abstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Psychosocial Vulnerabilities to Upper Respiratory Infectious Illness: Implications for Susceptibility to Coronavirus Disease 2019 (COVID-19).Perspectives on psychological science : a journal of the Association for Psychological Science · 2021
    Article
  2. Article
  3. Article
  4. Viral challenge reveals further evidence of skin-deep resilience in African Americans from disadvantaged backgrounds.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2016
    Article
  5. Article
  6. Review
  7. Nasal lavage VEGF and TNF-α levels during a natural cold predict asthma exacerbations.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2014
    Article
  8. Article
  9. Cytokine polymorphisms predict the frequency of otitis media as a complication of rhinovirus and RSV infections in children.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2009
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William J DoyleAllegheny Hospital, 320 East North Avenue, Pittsburgh, PA 15212, USA.
David P Skoner
Deborah Gentile

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identification of a pharmacologically targeted mediator of the common cold is a desirable, but, to date, elusive goal of current research. The roles of various mediators, such as histamine, leukotrienes, bradykinin, and, more recently, chemokines and cytokines, in the pathophysiology and development of complications of the common cold are the subject of previous and current investigations. Establishing causality of a mediator in the common cold has been difficult for a number of reasons, including the limitations of our research tools and protocols and the complexity of the inflammatory and immune pathways that participate during the common cold. The available evidence for mediation of the common cold is the subject of this manuscript.

Indexed as

Common ColdCytokinesHumansNasal MucosaSignal TransductionCytokines

Identifiers

PMID15842953
PMCPMC7089508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.