Evidence map›Paper›PMID 15842546›Full record

ArticleBritish journal of clinical pharmacology2005

Biomarkers and surrogate endpoints.

J K Aronson

Abstract readEditorial
In one paragraph

Article in British journal of clinical pharmacology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Expedited regulatory approval pathways for novel oncology drugs.Medical oncology (Northwood, London, England) · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Targeting collagen to optimize cancer immunotherapy.Experimental hematology & oncology · 2025
    Review
  8. Review
  9. Characterizing circulating biomarkers for childhood dementia disorders: A scoping review of clinical trials.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Using biomarkers to allocate patients in a response-adaptive clinical trial.Communications in statistics: Simulation and computation · 2023
    Article
  14. Review
  15. Recent Trends in Lateral Flow Immunoassays with Optical Nanoparticles.International journal of molecular sciences · 2023
    Review
  16. Demonstrating proof of concept for value-based agreements in Europe: two real-world cases.International journal of technology assessment in health care · 2023
    Article
  17. Review
  18. Article
  19. Review
  20. Review

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

J K Aronson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersCosts and Cost AnalysisHumansBiomarkers

Identifiers

PMID15842546
PMCPMC1884846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.