ArticleVirchows Archiv : an international journal of pathology2005
Pyloric gland adenoma arising in Barrett's esophagus with mucin immunohistochemical and molecular cytogenetic evaluation.
Article in Virchows Archiv : an international journal of pathology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Clinicopathological characteristics of 30 cases of pyloric gland adenoma: a single center case series.BMC gastroenterology · 2025Article
- Multifocal Pyloric Gland Adenoma of the Esophagus Treated by Circumferential Endoscopic Submucosal Dissection.ACG case reports journal · 2023Article
- Pyloric Gland Adenoma of the Esophagus Treated by Endoscopic Submucosal Dissection: A Case Report.Gut and liver · 2022Article
- Gastric pyloric gland adenoma resembling a submucosal tumor: A case report.World journal of clinical cases · 2020Article
- BOB CAT: A Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia.The American journal of gastroenterology · 2015Review
- Pyloric gland adenoma: a case report.Case reports in gastroenterology · 2013Article
- Pyloric gland adenoma of the cystic duct with malignant transformation: report of a case with a review of the literature.BMC cancer · 2012Article
- The role of mucin in GERD and its complications.Nature reviews. Gastroenterology & hepatology · 2011Article
- Duodenal adenocarcinoma arising from a pyloric gland adenoma with a brief review of the literature.BMJ case reports · 2010Review
- [Tubular adenoma of the stomach with special reference to the Japanese criteria and pyloric gland adenoma].Der Pathologe · 2010Article
- Alterations in mucin expression in ovarian mucinous tumors: immunohistochemical analysis of MUC2, MUC5AC, MUC6, and CD10 expression.Acta histochemica et cytochemica · 2008Article
- Gastric-type well-differentiated adenocarcinoma and pyloric gland adenoma of the stomach.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2006Review
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyloric gland adenoma is a recently described and very rare entity. The occurrence of adenoma is very unusual in Barrett's epithelium of the esophagus. We report a case of esophageal polyp showing the features of pyloric gland adenoma, which was surrounded by so-called specialized columnar epithelium. Immunohistochemically, most tumor glands were strongly positive for MUC6, except in the superficial layer. MUC5AC was positive in almost all tumor cells, but MUC2 and CD10 were negative in the tumor. MIB-1-positive proliferating cells were distributed throughout the tumor. Microdissection and comparative genomic hybridization analyses revealed losses on 2p24-25.2, 2q14.1-ter, 5q31.3-32, 6q23-24, 8q23-24.2, 11q22.3-24 and 18q21.1-22. This is the first case of pyloric gland adenoma found to arise in Barrett's epithelium of the esophagus, showing its unstable and precancerous nature.
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