ReviewJournal of mammary gland biology and neoplasia2004
Strategies for engineering the adhesive microenvironment.
Review in Journal of mammary gland biology and neoplasia, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Nanoengineered Platforms to Guide Pluripotent Stem Cell Fate.Journal of nanomedicine & nanotechnology · 2014Article
- Overview of micro- and nano-technology tools for stem cell applications: micropatterned and microelectronic devices.Sensors (Basel, Switzerland) · 2012Review
- Contact printing of arrayed microstructures.Analytical and bioanalytical chemistry · 2010Article
- Modulation of hepatocarcinoma cell morphology and activity by parylene-C coating on PDMS.PloS one · 2010Article
- Presentation counts: microenvironmental regulation of stem cells by biophysical and material cues.Annual review of cell and developmental biology · 2010Review
- Controlled differentiation of stem cells.Advanced drug delivery reviews · 2008Review
- Screening the cellular microenvironment: a role for microfluidics.IEEE reviews in biomedical engineering · 2008Review
- High-throughput analysis of signals regulating stem cell fate and function.Current opinion in chemical biology · 2007Review
- Receptor-mediated and intrinsic polarization and their interaction in chemotaxing cells.Biophysical journal · 2007Article
- A bioreactor model of mouse tumor progression.Journal of biomedicine & biotechnology · 2007Article
- Regulation of cancer invasiveness by the physical extracellular matrix environment.Cell adhesion & migrationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Cells exist within a complex tissue microenvironment, which includes soluble factors, extracellular matrix molecules, and neighboring cells. In the breast, the adhesive microenvironment plays a crucial role in driving both normal mammary gland development as well tumor initiation and progression. Researchers are designing increasingly more complex ways to mimic the in vivo microenvironment in an in vitro setting, so that cells in culture may serve as model systems for tissue structures. Here, we explore the use of microfabrication technologies to engineer the adhesive microenvironment of cells in culture. These new tools permit the culture of cells on well-defined surface chemistries, patterning of cells into defined geometries either alone or in coculture scenarios, and measurement of forces associated with cell-ECM interactions. When applied to questions in mammary gland development and neoplasia, these new tools will enable a better understanding of how adhesive, structural, and mechanical cues regulate mammary epithelial biology.
Indexed as
Identifiers
15838609What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.