ReviewAnnals of the New York Academy of Sciences2004
Neurobiology of rehabilitation.
Review in Annals of the New York Academy of Sciences, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04759326 (Neurorehabilitation Through Hippotherapy on Neurofunctional Sequels of Brain Stroke), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurorehabilitation Through Hippotherapy on Neurofunctional Sequels of Brain Stroke: (i) Effect on Patient's Functional Independence, Sensorimotor and Cognitive Capacities and Quality of Life (ii) Effect on Caregivers' Quality of Life
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.
- The Effect of Robotic Assisted Gait Training With Lokomat® on Balance Control After Stroke: Systematic Review and Meta-Analysis.Frontiers in neurology · 2021Pooled it
- Effects of robotic hand-assisted rehabilitation on motor function and daily living activities in acute stroke: a randomized controlled trial.Scientific reports · 2026Trial
- Effects of task complexity or rate of motor imagery on motor learning in healthy young adults.Brain and behavior · 2021Trial
- Aerobic exercise improves cognition and motor function poststroke.Neurorehabilitation and neural repair · 2009Trial
- Current insights into the management of spinal cord injury.Journal of orthopaedics · 2023Article
- Acquired Brain Injury in Adults: A Review of Pathophysiology, Recovery, and Rehabilitation.Perspectives of the ASHA special interest groups · 2021Article
- Novel innovations in cell and gene therapies for spinal cord injury.F1000Research · 2020Review
- Patient Engagement Is Related to Impairment Reduction During Digital Game-Based Therapy in Stroke.Games for health journal · 2017Article
- Differences in muscle activity and temporal step parameters between Lokomat guided walking and treadmill walking in post-stroke hemiparetic patients and healthy walkers.Journal of neuroengineering and rehabilitation · 2017Article
- The Effects of Modified Constraint-Induced Movement Therapy in Acute Subcortical Cerebral Infarction.Frontiers in human neuroscience · 2017Article
- Brain stimulation: Neuromodulation as a potential treatment for motor recovery following traumatic brain injury.Brain research · 2016Review
- Excitability properties of motor axons in adults with cerebral palsy.Frontiers in human neuroscience · 2015Article
- Major unsolved points in adult neurogenesis: doors open on a translational future?Frontiers in neuroscience · 2014Article
- Molecular and cellular changes in the lumbar spinal cord following thoracic injury: regulation by treadmill locomotor training.PloS one · 2014Article
- Animal models of post-ischemic forced use rehabilitation: methods, considerations, and limitations.Experimental & translational stroke medicine · 2013Article
- Guest editorial: emergent themes from second annual symposium on regenerative rehabilitation, Pittsburgh, Pennsylvania.Journal of rehabilitation research and development · 2013Article
- Non-invasive brain stimulation in neglect rehabilitation: an update.Frontiers in human neuroscience · 2013Article
- Epidural cortical stimulation and aphasia therapy.Aphasiology · 2012Article
- Fractional anisotropy and mean diffusivity in the corpus callosum of patients with multiple sclerosis: the effect of physiotherapy.Neuroradiology · 2011Article
- Combining Brain-Computer Interfaces and Assistive Technologies: State-of-the-Art and Challenges.Frontiers in neuroscience · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Rehabilitation aims to lessen the physical and cognitive impairments and disabilities of patients with stroke, multiple sclerosis, spinal cord or brain injury, and other neurologic diseases. Conventional approaches beyond compensatory adjustments to disability may be augmented by applying some of the myriad experimental results about mechanisms of intrinsic biological changes after injury and the effects of extrinsic manipulations on spared neuronal assemblies. The organization and inherent adaptability of the anatomical nodes within distributed pathways of the central nervous system offer a flexible substrate for treatment strategies that drive activity-dependent plasticity. Opportunities for a new generation of approaches are manifested by rodent and non-human primate studies that reveal morphologic and physiologic adaptations induced by injury, by learning-associated practice, by the effects of pharmacologic neuromodulators, by the behavioral and molecular bases for enhancing activity-dependent synaptic plasticity, and by cell replacement, gene therapy, and regenerative biologic strategies. Techniques such as functional magnetic resonance imaging and transcranial magnetic stimulation will help determine the most optimal physiologic effects of interventions in patients as the cortical representations for skilled movements and cognitive processes are modified by the combination of conventional and biologic therapies. As clinicians digest the finer details of the neurobiology of rehabilitation, they will translate laboratory data into controlled clinical trials. By determining how much they can influence neural reorganization, clinicians will extend the opportunities for neurorestoration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.