ArticleProceedings of the National Academy of Sciences of the United States of America2005
A coiled-coil interaction mediates cauliflower mosaic virus cell-to-cell movement.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 65 citations in OpenAlex.
- Five questions on the cell-to-cell movement ofBBA advances · 2024Article
- An Evolved 5' Untranslated Region of Alfalfa Mosaic Virus Allows the RNA Transport of Movement-Defective Variants.Journal of virology · 2022Article
- Genetic differences between Korean and American isolates of Petunia vein clearing virus.Virus genes · 2020Article
- Dissecting the Subcellular Localization, Intracellular Trafficking, Interactions, Membrane Association, and Topology of Citrus Leprosis Virus C Proteins.Frontiers in plant science · 2018Article
- Interactions Between Drought and Plant Genotype Change Epidemiological Traits ofFrontiers in plant science · 2018Article
- The proposed new species, cacao red vein virus, and three previously recognized badnavirus species are associated with cacao swollen shoot disease.Virology journal · 2017Article
- Setting Up Shop: The Formation and Function of the Viral Factories ofFrontiers in plant science · 2017Review
- Cauliflower mosaic virus Transcriptome Reveals a Complex Alternative Splicing Pattern.PloS one · 2015Article
- Association of the P6 protein of Cauliflower mosaic virus with plasmodesmata and plasmodesmal proteins.Plant physiology · 2014Article
- Hitching a ride on vesicles: cauliflower mosaic virus movement protein trafficking in the endomembrane system.Plant physiology · 2014Article
- Groundnut bud necrosis virus encoded NSm associates with membranes via its C-terminal domain.PloS one · 2014Article
- The Arabidopsis synaptotagmin SYTA regulates the cell-to-cell movement of diverse plant viruses.Frontiers in plant science · 2014Article
- Virus factories of cauliflower mosaic virus are virion reservoirs that engage actively in vector transmission.Journal of virology · 2013Article
- Cauliflower mosaic virus major inclusion body protein interacts with the aphid transmission factor, the virion-associated protein, and gene VII product.Virus research · 2012Article
- Top 10 plant viruses in molecular plant pathology.Molecular plant pathology · 2011Review
- Intracellular transport of plant viruses: finding the door out of the cell.Molecular plant · 2011Review
- Excision and episomal replication of cauliflower mosaic virus integrated into a plant genome.Plant physiology · 2011Article
- A family of plasmodesmal proteins with receptor-like properties for plant viral movement proteins.PLoS pathogens · 2010Article
- Structural insights into the molecular mechanisms of cauliflower mosaic virus transmission by its insect vector.Journal of virology · 2010Article
- Caulimoviridae tubule-guided transport is dictated by movement protein properties.Journal of virology · 2010Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The function of the virion-associated protein (VAP) of cauliflower mosaic virus (CaMV) has long been only poorly understood. VAP is associated with the virion but is dispensable for virus morphogenesis and replication. It mediates virus transmission by aphids through simultaneous interaction with both the aphid transmission factor and the virion. However, although insect transmission is not fundamental to CaMV survival, VAP is indispensable for spreading the virus infection within the host plant. We used a GST pull-down technique to demonstrate that VAP interacts with the viral movement protein through coiled-coil domains and surface plasmon resonance to measure the interaction kinetics. We mapped the movement protein coiled-coil to the C terminus of the protein and proved that it self-assembles as a trimer. Immunogold labeling/electron microscopy revealed that the VAP and viral movement protein colocalize on CaMV particles within plasmodesmata. These results highlight the multifunctional potential of the VAP protein conferred by its efficient coiled-coil interaction system and show a plant virus possessing a surface-exposed protein (VAP) mediating viral entry into host cells.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.