ArticleJournal of comparative physiology. A, Sensory, neural, and behavioral physiology1992
The stopping response of Xenopus laevis embryos: behaviour, development and physiology.
Article in Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 50 citations in OpenAlex.
- Structural field margin characteristics affect the functional traits of herbaceous vegetation.PloS one · 2020Article
- Growth at Cold Temperature Increases the Number of Motor Neurons to Optimize Locomotor Function.Current biology : CB · 2019Article
- Integration of Descending Command Systems for the Generation of Context-Specific Locomotor Behaviors.Frontiers in neuroscience · 2017Review
- A behaviorally related developmental switch in nitrergic modulation of locomotor rhythmogenesis in larval Xenopus tadpoles.Journal of neurophysiology · 2016Article
- Ontogenetic Development of Vestibulo-Ocular Reflexes in Amphibians.Frontiers in neural circuits · 2016Review
- Modelling Feedback Excitation, Pacemaker Properties and Sensory Switching of Electrically Coupled Brainstem Neurons Controlling Rhythmic Activity.PLoS computational biology · 2016Article
- Sensory Activation of Command Cells for Locomotion and Modulatory Mechanisms: Lessons from Lampreys.Frontiers in neural circuits · 2016Review
- Behavioral observation of Xenopus tadpole swimming for neuroscience labs.Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2014Article
- Conservation, development, and function of a cement gland-like structure in the fish Astyanax mexicanus.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- touché Is required for touch-evoked generator potentials within vertebrate sensory neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- BDNF promotes target innervation of Xenopus mandibular trigeminal axons in vivo.BMC developmental biology · 2007Article
- Metamodulation of a spinal locomotor network by nitric oxide.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Brainstem control of activity and responsiveness in resting frog tadpoles: tonic inhibition.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2004Article
- The neuronal targets for GABAergic reticulospinal inhibition that stops swimming in hatchling frog tadpoles.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2003Article
- Nitric oxide selectively tunes inhibitory synapses to modulate vertebrate locomotion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Sensory activation and role of inhibitory reticulospinal neurons that stop swimming in hatchling frog tadpoles.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
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Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. When Xenopus laevis embryos swim into an obstruction they usually stop. This stopping response to stimulation on the head is present from stage 28 to 45. At stage 37/38 it is more reliable in restrained than in free-swimming animals, and to stimuli to the cement gland than to the head skin. 'Fictive' swimming also stops reliably after the same stimuli but struggling and 'fictive' struggling do not. 2. Discharge of deformation-sensitive trigeminal sensory neurons in response to pressure on the cement gland or head skin precedes the 'fictive' stopping response. When the embryo hangs from cement gland mucus, trigeminal neurons are active and the embryo is less responsive to stimulation. 3. Lesions of the central nervous system have allowed us to draw the following conclusions about this inhibitory pathway: (a) either the cement gland or the head skin must be intact; (b) one trigeminal ganglion is both sufficient and necessary; (c) the pathway is independent of the forebrain and midbrain; (d) it can take an ipsilateral or contralateral route through the hindbrain; (e) at least two hindbrain interneuron components are involved. 4. A similar stopping response is present in embryos and larvae of the urodele Ambystoma mexicanum.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.