ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2005
Intracranial aneurysms in children aged under 15 years: review of 59 consecutive children with 75 aneurysms.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 6 of them syntheses that pooled it.
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91 citing papers in PubMed, 6 syntheses or guidelines pooled it, 274 citations in OpenAlex.
- Treatment of pediatric intracranial aneurysms: institutional case series and systematic literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Pooled it
- A systematic review of prenatally diagnosed vein of Galen malformations: prenatal predictive markers and management from fetal life to childhood.Frontiers in pediatrics · 2024Pooled it
- Posttraumatic cerebrovascular injuries in children. A systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Pooled it
- Treatment and outcome of thrombosed aneurysms of the middle cerebral artery: institutional experience and a systematic review.Neurosurgical review · 2019Pooled it
- Endovascular versus Non-Interventional Therapy for Cervicocranial Artery Dissection in East Asian and Non-East Asian Patients: a Systematic Review and Meta-analysis.Scientific reports · 2015Pooled it
- Intracranial aneurysms in children under 1 year of age: a systematic review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2006Pooled it
- Article
- Intracranial mycotic aneurysms in pediatric patients: A systematic review.Surgical neurology international · 2026Review
- Ruptured posterior inferior cerebellar artery aneurysm in a neonate treated with coil embolization: A technical report.Surgical neurology international · 2026Article
- Survival of a 2-month-old infant after clipping of ruptured middle cerebral artery aneurysm: A case report and review of the literature.Surgical neurology international · 2026Article
- Can a child survive a basilar artery injury during endoscopic third ventriculostomy? case-based review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- Giant dissecting aneurysm of basilar artery in a child - treated by flow reversal: A case report.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Endovascular management of a ruptured complex ACoM aneurysm in a 9-month-old infant: a rare case report and literature review.Neuroradiology · 2025Review
- Unveiling diagnostic challenges and therapeutic triumphs: endovascular management of a paediatric internal carotid artery pseudoaneurysm-a case report.European heart journal. Case reports · 2025Article
- Vein of Galen aneurysmal malformations: retrospective evaluation of endovascular treatment outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Endovascular therapeutic occlusion of major cerebral arteries in children.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Ruptured distal middle cerebral artery aneurysm in a pediatric patient: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Endovascular treatment of pediatric ruptured intracranial dissecting aneurysm: a case report and literature review.Frontiers in surgery · 2025Article
- Embolization of dissected and ruptured giant anterior cerebral artery aneurysm in a full-term neonate.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Review
- Emergency microsurgical trapping, decompression, and revascularization of a middle cerebral artery dissecting aneurysm using a minipterional approach in a pediatric patient: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
31 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective was to review the clinical aspects and therapeutic strategies in a series of aneurysmal vasculopathies seen in children 15 years or under.
methodsFrom our dedicated neurovascular databank of patients, we reviewed 59 consecutive children who had 75 separate lesions.
resultsThe children were divided into four age groups: below 2 years (22%), 2-5 years (24%), 6-10 years (24%) and 11-15 years (30%). Thirty-three children had dissecting aneurysms, 2 had chronic post-traumatic aneurysms, 8 had infectious aneurysms and 16 had saccular lesions. Twenty-seven percent of the lesions were in the posterior circulation, and 21% developed on the middle cerebral artery. Most dissecting lesions were encountered in the vertebrobasilar system, while saccular lesions were present mostly in the anterior circulation. Half of all cases presented with haemorrhage. Haemorrhage in patients below 2 years of age was due to dissecting aneurysms, while saccular aneurysms were responsible for haemorrhage in patients above 5 years of age. Five children had familial disease and 9 presented with multiple aneurysms. Forty-eight children were referred to us for treatment. Thirty-two underwent surgical (21.9%), endovascular (62.8%) or combined (9.3%) treatment. Eleven patients were treated conservatively and in 5 patients the aneurysms had spontaneously thrombosed at admission. Overall, complete or partial spontaneous thrombosis was seen in 10 patients (16.9%). Dissecting aneurysms were frequent in children of all ages with either associated thrombosis or arterial tear with repeated acute haemorrhage and poor outcome. Two types of dissection seem identifiable despite the small number of cases collected: acute segmental arterial tear without thrombosis, acute subarachnoid haemorrhage (SAH) and recurrence before 5 years; and subacute focal dissection with partial thrombosis (or mural haematoma), rare SAH and no early recurrence. The former would require aggressive management whereas the latter often do not require interventional approaches. The mortality in our series of aneurysms is low in the treated group (10.42%). The overall tolerance to haemorrhage seems better than in adults, as already stressed in the literature.
conclusionThe multiple etiologies encountered confirm the heterogenous nature of "aneurysms". The variety of treatments used suggests the need to categorise aneurysms into subgroups in sufficient numbers to fully appreciate the behavior of the lesions and make the appropriate therapeutic decisions.
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