Evidence map›Paper›PMID 15830157›Full record

ArticleVirus genes2005

Molecular phylogenetic analysis of Iranian HDV complete genome.

Farida Behzadian, Farzaneh Sabahi, Mohsen Karimi, Majid Sadeghizadeh, Nader Maghsoudi, Ramin Sarrami Forooshani, Leila Shahinsaz

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Article in Virus genes, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Hepatitis D Virus-Specific CD8Gastroenterology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Farida BehzadianDepartment of Virology, School of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran, Iran.
Farzaneh Sabahi
Mohsen Karimi
Majid Sadeghizadeh
Nader Maghsoudi
Ramin Sarrami Forooshani
Leila Shahinsaz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis D (delta) virus (HDV) is a subviral pathogen agent and a satellite of Hepatitis B virus. Three distinct genotypes are described for HDV; genotype I is distributed worldwide but other genotypes appear to be more restricted geographically. In the present study, the entire nucleotide sequence of an HDV isolate from an Iranian patient (IR-1) was obtained using twelve pairs of primers to amplify six overlapping fragments covering the whole HDV genome by RT-nested PCR. Phylogenetic and pairwise alignments were done on this new isolate to determine IR-1 position among other isolates. Our results indicate that IR-1 contains 1676 nucleotides encoding 214 a.a. of the hepatitis delta antigen (HDAg). This new isolate belongs to genotype I with most sequence similarity to an Italian HDV isolate (92.6%). At amino acid level, predicted HDAg sequence of IR-1 revealed the most homology with those of Italian and Lebanese isolates. Data analysis confirmed genetic variability and heterogeneity of the HDV species isolated from different geographical areas.

Indexed as

Genome, ViralAdultAmino Acid SequenceAntigens, ViralBase SequenceGenetic VariationHepatitis DHepatitis Delta VirusHumansIranMaleMolecular Sequence DataPhylogenyRNA, ViralSequence AlignmentSequence HomologyAntigens, ViralRNA, Viral

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.