Evidence map›Paper›PMID 15829012›Full record

ReviewRetrovirology2005

Intracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.

Yong-Hui Zheng, B Matija Peterlin

Abstract readReview
In one paragraph

Review in Retrovirology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yong-Hui ZhengDepartment of Medicine, Rosalind Russell Arthritis Research Center, University of California, San Francisco, CA 94143-0703, USA. yonghui@itsa.ucsf.edu
B Matija Peterlin

Funding

Roles of N-TEF and P-TEBb in HIV LatencyP01AI058708 · NIAID · J. DAVID GLADSTONE INSTITUTES · PI VERDIN, ERIC M. · 2004 to 2009
$11.6M
TAT TransactivationR01AI049104 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PETERLIN, BORIS MATIJA · 2001 to 2015
$5.3M
NIAID NIH HHS P01 AI058708NIAID NIH HHS R01 AI049104NIAID NIH HHS R01 AI49104PHS HHS R01 A151165
6 · The paper itself

Abstract

Studies of the human immunodeficiency virus type 1 (HIV-1) continue to enrich eukaryotic biology and immunology. Recent advances have defined factors that function after viral entry and prevent the replication of proviruses in the infected cell. Some of these attack directly viral structures whereas others edit viral genetic material during reverse transcription. Together, they provide strong and immediate intracellular immunity against incoming pathogens. These processes also offer a tantalizing glimpse at basic cellular mechanisms that might restrict the movement of mobile genetic elements and protect the genome.

Indexed as

AnimalsAntiviral Restriction FactorsCarrier ProteinsCell LineCytosine DeaminaseHIV-1HIV InfectionsHumansMiceMice, Inbred BALB CRatsTripartite Motif ProteinsUbiquitin-Protein LigasesVirus ReplicationAntiviral Restriction FactorsCarrier ProteinsCytosine DeaminaseTRIM5 protein, humanTripartite Motif ProteinsUbiquitin-Protein Ligases

Identifiers

PMID15829012
PMCPMC1131925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.