ArticleJournal of neurology2005
Peripheral neuropathy in CADASIL.
Article in Journal of neurology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 27 citations in OpenAlex.
- Persistent vessel wall enhancement and progression of cerebral microbleeds in CADASIL: a case report.Frontiers in radiology · 2026Article
- Article
- The pericyte: A critical cell in the pathogenesis of CADASIL.Cerebral circulation - cognition and behavior · 2021Review
- Peripheral neuropathy in a case with CADASIL: a case report.BMC neurology · 2018Article
- Review
- Nerve conduction studies in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.Journal of neurology · 2009Article
- Neuropsychiatric manifestations in CADASIL.Dialogues in clinical neuroscience · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a hereditary cerebral microangiopathy associated with mutations in the Notch 3 gene. The clinical phenotype is characterized by cerebral impairment even though typical microvascular changes are diffuse.
objectiveTo assess peripheral neuropathy in patients with CADASIL. PATIENTS AND
methodsWe enrolled eleven CADASIL patients with variable phenotype including clinical signs of peripheral nerve involvement. In all patients electromyography and nerve conduction velocities were performed. Peripheral nerve biopsy was performed in three cases.
resultsWe found sensory motor neuropathy in 7/11 patients. Nerve biopsy revealed axonal and demyelinated findings.
conclusionOur findings suggest that peripheral neuropathy may be part of the CADASIL phenotype.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.