ArticleInternational archives of occupational and environmental health2005
Effects of shift work on QTc interval and blood pressure in relation to heart rate variability.
Article in International archives of occupational and environmental health, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Unlocking the potential of circadian biology for cardiovascular health.Physiological reviews · 2026Review
- Influence of Night Shift Work on Heart Rate Variability in an Age- and Gender-Matched Study Group.Journal of cardiovascular development and disease · 2024Article
- Circadian disruptions and their role in the development of hypertension.Frontiers in neuroscience · 2024Review
- Circadian Disruption and the Molecular Clock in Atherosclerosis and Hypertension.The Canadian journal of cardiology · 2023Review
- Sympathoexcitatory responses to renal chemosensitive stimuli are exaggerated at nighttime in rats.American journal of physiology. Heart and circulatory physiology · 2022Article
- Article
- Multi-Scale Evaluation of Sleep Quality Based on Motion Signal from Unobtrusive Device.Sensors (Basel, Switzerland) · 2022Article
- Evaluation of ECG Repolarization Parameters in a Worker Cohort Working the Night Shift.Journal of the Saudi Heart Association · 2022Article
- Effect of noise on the electrocardiographic parameters.International archives of occupational and environmental health · 2021Article
- Shift Workers Have Higher Blood Pressure Medicine Use, But Only When They Are Short Sleepers: A Longitudinal UK Biobank Study.Journal of the American Heart Association · 2019Article
- Impact of Circadian Disruption on Cardiovascular Function and Disease.Trends in endocrinology and metabolism: TEM · 2019Review
- Clinical significance of stress-related increase in blood pressure: current evidence in office and out-of-office settings.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Review
- The relationship between shift work and Framingham risk score: A five-year prospective cohort study.ARYA atherosclerosis · 2017Article
- Metabolomic patterns associated to QTc interval in shiftworkers: an explorative analysis.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2016Article
- Consequences of Circadian Disruption on Cardiometabolic Health.Sleep medicine clinics · 2015Review
- Multicenter historical cohort study of the relationship between shift work and blood pressure.ARYA atherosclerosis · 2014Article
- Historical cohort study on the factors affecting blood pressure in workers of polyacryl iran corporation using bayesian multilevel modeling with skew T distribution.Iranian Red Crescent medical journal · 2013Article
- Circadian adaptation to night shift work influences sleep, performance, mood and the autonomic modulation of the heart.PloS one · 2013Article
- Neurobehavioral deficits and increased blood pressure in school-age children prenatally exposed to pesticides.Environmental health perspectives · 2010Article
- Subclinical effects of prenatal methylmercury exposure on cardiac autonomic function in Japanese children.International archives of occupational and environmental health · 2006Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThere is evidence that shift work contributes to excess cardiovascular mortality. The purpose of this study was to determine the effects of shift work on heart rate-corrected QT (QTc) and blood pressure in relation to heart rate variability (CV(RR)).
methodsThe study population consisted of 153 male shiftworkers and 87 male day workers who were employed at a copper-smelting plant. The QTc interval, total power spectral density (t-PSD) of 100 RR intervals, PSDs with frequencies of 0.01 Hz-0.15 Hz and 0.15 Hz-0.40 Hz (PSD(LF) and PSD(HF)), CV(RR), low frequency (LF) component variability and high frequency (HF) component variability (CCV(LF) and CCV(HF)) and %LF (PSD(LF)/(PSD(LF)+PSD(HF)) .100) were measured (LF and HF components are thought to reflect the sympathetic and parasympathetic activities, respectively).
resultsThe QTc interval was significantly longer in the shiftworkers than in the day workers, although there was no significant difference in systolic or diastolic blood pressure between the two groups. Also, the CCV(LF) and log(PSD(LF)) were significantly depressed in the shiftworkers. In the day workers, the QTc interval was significantly related to the CV(RR), log(t-PSD), CCV(HF), log(PSD(HF)),%LF, and log(LF/HF ratio) (partial correlation coefficient r=-0.305, -0.377, -0.312, -0.355, 0.297, and 0.277, respectively). In the shiftworkers only two relations of the QTc interval to non-specific CV(RR) and log(t-PSD) were significant.
conclusionThe clear association between long QTc interval and reduced parasympathetic activity observed in the day workers did not exist in the shiftworkers. Rather, the shiftworkers had a selective reduction in sympathetic drive, which may have compensated for prolonged QTc interval due to shift work. On the other hand, the impact of shift work on hypertension remains unclear, although reduced sympathetic drive in the shiftworkers may explain the absence of differences in blood pressure between shiftworkers and day workers to some extent.
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