ArticlePlant molecular biology2004
Molecular characterization of a WEE1 gene homologue in tomato (Lycopersicon esculentum Mill.).
Article in Plant molecular biology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Regulation of cell cycle in plant gametes: when is the right time to divide?Development (Cambridge, England) · 2025Review
- Jasmonates, gibberellins, and powdery mildew modify cell cycle progression and evoke differential spatiotemporal responses along the barley leaf.Journal of experimental botany · 2024Article
- Article
- Genome-Wide Analysis of the YABBY Gene Family in Grapevine and Functional Characterization ofFrontiers in plant science · 2019Article
- PEG Induces High Expression of the Cell Cycle Checkpoint GeneFrontiers in plant science · 2017Article
- Arabidopsis thaliana RNase H2 deficiency counteracts the needs for the WEE1 checkpoint kinase but triggers genome instability.The Plant cell · 2014Article
- Control of the meiotic cell division program in plants.Plant reproduction · 2013Review
- Plant WEE1 kinase is cell cycle regulated and removed at mitosis via the 26S proteasome machinery.Journal of experimental botany · 2013Article
- Identification of a Wee1-like kinase gene essential for procyclic Trypanosoma brucei survival.PloS one · 2013Article
- Perturbation of cytokinin and ethylene-signalling pathways explain the strong rooting phenotype exhibited by Arabidopsis expressing the Schizosaccharomyces pombe mitotic inducer, cdc25.BMC plant biology · 2012Article
- A role of tomato UV-damaged DNA binding protein 1 (DDB1) in organ size control via an epigenetic manner.PloS one · 2012Article
- Elucidating the functional role of endoreduplication in tomato fruit development.Annals of botany · 2011Review
- Regulatory dephosphorylation of CDK at G₂/M in plants: yeast mitotic phosphatase cdc25 induces cytokinin-like effects in transgenic tobacco morphogenesis.Annals of botany · 2011Article
- Expression profiling of cell cycle genes reveals key facilitators of cell production during carpel development, fruit set, and fruit growth in apple (Malusxdomestica Borkh.).Journal of experimental botany · 2011Article
- The regulatory network of cell-cycle progression is fundamentally different in plants versus yeast or metazoans.Plant signaling & behavior · 2010Article
- Control of cell proliferation, organ growth, and DNA damage response operate independently of dephosphorylation of the Arabidopsis Cdk1 homolog CDKA;1.The Plant cell · 2009Article
- Global gene expression analysis of apple fruit development from the floral bud to ripe fruit.BMC plant biology · 2008Article
- Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint.The Plant cell · 2007Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early fruit development in tomato (Lycopersicon esculentum Mill.) proceeds in two distinct phases of growth that comprise cell division and cell expansion, respectively. In pericarp and the jelly like locular tissue of tomato fruit, the transition between cell division to cell expansion is characterized by the arrest of mitotic activity, numerous rounds of nuclear DNA endoreduplication and the inhibition of Cyclin-Dependent Kinase A (CDKA) activity. To investigate whether the WEE1 kinase may play a role during the endoreduplication process, we isolated and characterized the tomato homologue for WEE1. The LeWEE1 gene consisted of 10 exons with a predicted 510 amino acid-long protein. The accumulation of the corresponding transcripts was associated with mitotically active organs: developing fruits, seeds and roots. Interestingly, LeWEE1was expressed in the jelly like locular tissue concomitant with endoreduplication during fruit development. Using tobacco BY-2 synchronized cells, we showed that the WEE1 gene expression is cell-cycle regulated with a maximum transcript accumulation at S phase. Our data indicate the putative dual contribution of LeWEE1 in the classical cell cycle and the endocycle.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.