ArticleNucleic acids research2005
Vertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.
Article in Nucleic acids research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 168 citations in OpenAlex.
- Discovery of a G-rich ultra stable human ncRNA G-quadruplex that binds ATP.Non-coding RNA research · 2026Article
- Structural effects of inosine substitution in telomeric DNA quadruplex.Frontiers in chemistry · 2024Article
- Thermally Induced Transitions of d(GLife (Basel, Switzerland) · 2022Article
- Ruthenium(II) Polypyridyl Complexes and Their Use as Probes and Photoreactive Agents for G-quadruplexes Labelling.Molecules (Basel, Switzerland) · 2022Review
- Binding of BRACO19 to a Telomeric G-Quadruplex DNA Probed by All-Atom Molecular Dynamics Simulations with Explicit Solvent.Molecules (Basel, Switzerland) · 2019Article
- Evidence for a quadruplex structure in the polymorphic hs1.2 enhancer of the immunoglobulin heavy chain 3' regulatory regions and its conservation in mammals.Biopolymers · 2016Article
- Metal Cations in G-Quadruplex Folding and Stability.Frontiers in chemistry · 2016Review
- Formation and stabilization of the telomeric antiparallel G-quadruplex and inhibition of telomerase by novel benzothioxanthene derivatives with anti-tumor activity.Scientific reports · 2015Article
- Molecular dynamics and principal components of potassium binding with human telomeric intra-molecular G-quadruplex.Protein & cell · 2015Article
- Selection and Characterization of DNA Aptamers Targeting All Four Serotypes of Dengue Viruses.PloS one · 2015Article
- In-cell optical imaging of exogenous G-quadruplex DNA by fluorogenic ligands.Nucleic acids research · 2013Article
- A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex [d(TGGGGT)]4 and cyanine dye 2,2'-diethyl-9-methyl-selenacarbocyanine bromide.Nucleic acids research · 2013Article
- Polymorphism of human telomeric quadruplex structure controlled by DNA concentration: a Raman study.Nucleic acids research · 2013Article
- Ion-dependent conformational switching by a DNA aptamer that induces remyelination in a mouse model of multiple sclerosis.Nucleic acids research · 2013Article
- The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer.Bioorganic & medicinal chemistry · 2012Article
- Interaction of pyrrolobenzodiazepine (PBD) ligands with parallel intermolecular G-quadruplex complex using spectroscopy and ESI-MS.PloS one · 2012Article
- Kinetically governed polymorphism of d(G₄T₄G₃) quadruplexes in K+ solutions.Nucleic acids research · 2011Article
- Structure and stability of a dimeric g-quadruplex formed by cyclic oligonucleotides.Journal of nucleic acids · 2010Article
- Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs.Nucleic acids research · 2009Article
- Duplex formation at the 5' end affects the quadruplex conformation of the human telomeric repeat overhang in sodium but not in potassium.Biochemistry · 2009Article
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3 authors at 1 institution in 1 country.
Funding
Abstract
The circular dichroism, CD, spectra of the telomere repeats of vertebrates, d(TTAGGG), indicate that parallel type quadruplex structures or disordered single-stranded structures are formed in low salt. Anti-parallel quadruplex structures are favored in the presence of high concentrations, 140 mM, of sodium. External loop, also known as propeller, parallel type structures are favored in the presence of high concentrations, 100 mM, of potassium in the presence of either 5 or 140 mM sodium. The cation dependence of the CD spectra of the vertebrate telomere repeat DNAs is distinctly different from that of the telomere repeats of Tetrahymena and Oxytricha as well as that of the thrombin binding aptamer. These results indicate that the external loop structures may be present in vertebrate telomeres under the conditions of high potassium and low sodium concentration found in nuclei.
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