ArticlePlant cell reports2005
Mammalian Bax initiates plant cell death through organelle destruction.
Article in Plant cell reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
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- The wheat Sr8155B1 gene encodes a typical NLR protein that confers resistance to the Ug99 stem rust race group.Plant communications · 2025Article
- Cloning of the wheat leaf rust resistance gene Lr47 introgressed from Aegilops speltoides.Nature communications · 2023Article
- TAL effector-dependent Bax gene expression in transgenic rice confers disease resistance to Xanthomonas oryzae pv. oryzae.Transgenic research · 2022Article
- Characterization ofFrontiers in microbiology · 2021Article
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- Membrane-related hallmarks of kinetin-induced PCD of root cortex cells.Plant cell reports · 2017Article
- Expression of Arabidopsis Bax Inhibitor-1 in transgenic sugarcane confers drought tolerance.Plant biotechnology journal · 2016Article
- The Bax inhibitor MrBI-1 regulates heat tolerance, apoptotic-like cell death, and virulence in Metarhizium robertsii.Scientific reports · 2015Article
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- Co-immunoprecipitation-based identification of putative BAX INHIBITOR-1-interacting proteins involved in cell death regulation and plant-powdery mildew interactions.Molecular plant pathology · 2013Article
- The effect of translationally controlled tumour protein (TCTP) on programmed cell death in plants.BMC plant biology · 2013Article
- Determination of ACC-induced cell-programmed death in roots of Vicia faba ssp. minor seedlings by acridine orange and ethidium bromide staining.Protoplasma · 2013Article
- Reactive oxygen species as transducers of sphinganine-mediated cell death pathway.Plant signaling & behavior · 2011Article
- The Arabidopsis peptide kiss of death is an inducer of programmed cell death.The EMBO journal · 2011Article
- pH-sensitivity of YFP provides an intracellular indicator of programmed cell death.Plant methods · 2010Article
- Voltage-dependent anion channels: their roles in plant defense and cell death.Plant cell reports · 2009Review
- Plant voltage-dependent anion channels are involved in host defense against Pseudomonas cichorii and in Bax-induced cell death.Plant cell reports · 2009Article
- Mammalian pro-apoptotic bax gene enhances tobacco resistance to pathogens.Plant cell reports · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mammalian Bax is known to cause cell death when expressed in plants. We examined transgenic plants expressing both Bax and organelle-targeted green fluorescent protein to determine the cellular changes that occur during Bax-induced cell death. The mitochondria changed morphologically from being bacilli-shaped to being round, eventually becoming swollen. Mitochondria streaming also stopped. The chloroplasts lost membrane function and their contents leaked out, followed by the disruption of the vacuole. Light was not essential for Bax-induced ion leakage or organelle disruption. These results indicate that Bax induces temporal and spatial cell death events at the organelle level in the plant. A heterologous system, using Bax, would therefore be available to investigate cell death, which is commonly conserved in animals and plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.