Evidence map›Paper›PMID 15815044›Full record

ArticleJournal of clinical microbiology2005

Long-lasting CD3+ T-cell deficiency after cord blood stem cell transplantation in a human herpesvirus 6-infected child.

Manola Comar, Pierlanfranco D'Agaro, Douglas Horejsh, Monica Galvan, Simona Fiorentini, Marino Andolina, Arnaldo Caruso, Dario Di Luca, Cesare Campello

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Lymphoproliferative Syndromes Associated with Human Herpesvirus-6A and Human Herpesvirus-6B.Mediterranean journal of hematology and infectious diseases · 2018
    Review
  3. Article
  4. U94 of human herpesvirus 6 inhibits in vitro angiogenesis and lymphangiogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Manola ComarDepartment of Public Medicine Sciences, University of Trieste, Trieste, Italy.
Pierlanfranco D'Agaro
Douglas Horejsh
Monica Galvan
Simona Fiorentini
Marino Andolina
Arnaldo Caruso
Dario Di Luca
Cesare Campello
University of Trieste · ITUniversity of Brescia · ITUniversity of Ferrara · ITBrescia University · USIRCCS Materno Infantile Burlo Garofolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a long-lasting (8-month) reactivation of human herpesvirus 6 (HHV-6) infection in child who had undergone cord blood stem cell transplantation. The reactivation was characterized by high viral loads and by immediate-early mRNA positivity. HHV-6 infection was associated with a deep depletion of CD3, while the CD4/CD8 ratio remained substantially unchanged.

Indexed as

CD3 ComplexCD4-CD8 RatioChildCord Blood Stem Cell TransplantationHerpesvirus 6, HumanHumansImmunologic Deficiency SyndromesMaleRoseolovirus InfectionsT-LymphocytesVirus ActivationCD3 Complex

Identifiers

PMID15815044
PMCPMC1081381
OpenAlexW2121689767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.