Evidence map›Paper›PMID 15815027›Full record

ArticleJournal of clinical microbiology2005

Improvement of the specificity of an enzyme-linked immunosorbent assay for diagnosis of paracoccidioidomycosis.

C F Albuquerque, S H Marques da Silva, Z P Camargo

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Review
  3. Effects of metaperiodate and urea solutions on the serological diagnosis of human sporotrichosis using an indirect ELISA test.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2019
    Article
  4. Review
  5. Recombinant 60-kDa heat shock protein from Paracoccidioides brasiliensis: is it a good antigen for serological diagnosis of paracoccidioidomycosis?Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017
    Article
  6. Standardization and validation of Dot-ELISA assay forThe journal of venomous animals and toxins including tropical diseases · 2017
    Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

C F AlbuquerqueDepartment of Microbiology, Immunology and Parasitology, Cellular Biology Discipline, Federal University of São Paulo, Brazil.
S H Marques da Silva
Z P Camargo
Universidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an attempt to improve the specificity of an enzyme-linked immunosorbent assay (ELISA) for the diagnosis of paracoccidioidomycosis (PCM), sera from patients with PCM were tested using various approaches, such as sodium metaperiodate antigen (gp43) treatment, a serum absorption process with Candida albicans or Histoplasma capsulatum antigens, and dilution of serum in galactose, the main common epitope among pathogenic fungi. The maximum specificity found in this ELISA was 84%. All of these procedures proved inefficient for eliminating all cross-reacting antibodies and obtaining an ELISA specific for PCM diagnosis.

Indexed as

AbsorptionAntibodies, FungalAntigens, FungalCross ReactionsEnzyme-Linked Immunosorbent AssayFungal ProteinsGlycoproteinsHumansParacoccidioidesParacoccidioidomycosisPeriodic AcidSensitivity and Specificity43 kDa protein, ParacoccidioidesAntibodies, FungalAntigens, FungalFungal ProteinsGlycoproteinsmetaperiodatePeriodic Acid

Identifiers

PMID15815027
PMCPMC1081349
OpenAlexW2167718040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.