ArticleJournal of clinical microbiology2005
Analysis of the genetic structure of nontypeable pneumococcal strains isolated from conjunctiva.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Beneath the surface: a case report on nonencapsulatedAccess microbiology · 2024Article
- Review
- Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community.Scientific reports · 2021Article
- The Best of All Worlds:Microorganisms · 2019Review
- Review
- Nonencapsulated Streptococcus pneumoniae causes otitis media during single-species infection and during polymicrobial infection with nontypeable Haemophilus influenzae.Pathogens and disease · 2015Article
- Article
- Serotype 5 pneumococci causing invasive pneumococcal disease outbreaks in Barcelona, Spain (1997 to 2011).Journal of clinical microbiology · 2013Article
- Article
- Nontypeable pneumococcal isolates among navajo and white mountain apache communities: are these really a cause of invasive disease?The Journal of infectious diseases · 2012Article
- Novel molecular method for identification of Streptococcus pneumoniae applicable to clinical microbiology and 16S rRNA sequence-based microbiome studies.Journal of clinical microbiology · 2012Article
- Nontypeable Streptococcus pneumoniae as an otopathogen.Diagnostic microbiology and infectious disease · 2011Article
- Evidence of localized prophage-host recombination in the lytA gene, encoding the major pneumococcal autolysin.Journal of bacteriology · 2010Article
- Biofilm formation by Streptococcus pneumoniae: role of choline, extracellular DNA, and capsular polysaccharide in microbial accretion.Journal of bacteriology · 2006Article
- Characteristic signatures of the lytA gene provide a basis for rapid and reliable diagnosis of Streptococcus pneumoniae infections.Journal of clinical microbiology · 2006Article
- A successful, diverse disease-associated lineage of nontypeable pneumococci that has lost the capsular biosynthesis locus.Journal of clinical microbiology · 2006Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 50% of the nontypeable (NT) pneumococcal strains received in our laboratory for reference purposes are isolated in sporadic cases of conjunctivitis. To determine the genetic structure of the population of these NT conjunctival strains, we analyzed 75 pneumococci (40 NT and 35 typeable) isolated from conjunctivas and 30 (15 NT and 15 typeable) isolated from other sources. The NT and typeable conjunctival strains grouped in separate clusters, whereas NT and typeable pneumococci isolated from other sources were similarly distributed. NT conjunctival strains belonged to two well-differentiated clonal lineages. The first, represented by three newly described sequence types, featured fully antibiotic susceptible strains and appeared to be characteristic of conjunctival tissue; the second, represented by the previously described ST344, had a pattern of multiresistance to penicillin, tetracycline, and erythromycin and shared a genetic background with some NT strains isolated from other sources.
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