ArticleParticle and fibre toxicology2004
Cardiovascular effects in patrol officers are associated with fine particulate matter from brake wear and engine emissions.
Article in Particle and fibre toxicology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- The epidemiology of cancer among police officers.American journal of industrial medicine · 2013Pooled it
- A systematic review of occupational exposure to particulate matter and cardiovascular disease.International journal of environmental research and public health · 2010Pooled it
- A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability.Particle and fibre toxicology · 2014Trial
- Vehicle-Road Wear Microplastics: Fragmented Understanding of Their Impacts on Environment.Research (Washington, D.C.) · 2026Article
- Correlations between human alveolar macrophage particulate matter load, air pollution particulate matter levels, and systemic inflammation markers in Mexico City.Scientific reports · 2025Article
- Association between exposure to particulate matter and heart rate variability in vulnerable and susceptible individuals.NPJ digital medicine · 2025Article
- A Review of Road Traffic-Derived Non-Exhaust Particles: Emissions, Physicochemical Characteristics, Health Risks, and Mitigation Measures.Environmental science & technology · 2022Review
- The effect of emerging tobacco related products and their toxic constituents on thrombosis.Life sciences · 2022Review
- Vital roles of sustainable nano-fertilizers in improving plant quality and quantity-an updated review.Saudi journal of biological sciences · 2021Review
- Personal exposure to particulate matter and heart rate variability among informal electronic waste workers at Agbogbloshie: a longitudinal study.BMC public health · 2021Article
- Commuter exposure to particulate matter in urban public transportation of Xi'an, China.Journal of environmental health science & engineering · 2020Article
- South Asian Health: Inflammation, Infection, Exposure, and the Human Microbiome.Journal of immigrant and minority health · 2019Review
- Ischemic Heart Disease Mortality and Diesel Exhaust and Respirable Dust Exposure in the Diesel Exhaust in Miners Study.American journal of epidemiology · 2018Article
- Mobile Measurements of Particulate Matter in a Car Cabin: Local Variations, Contrasting Data from Mobile versus Stationary Measurements and the Effect of an Opened versus a Closed Window.International journal of environmental research and public health · 2018Article
- Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation.Archives of toxicology · 2018Article
- In-Cabin Air Quality during Driving and Engine Idling in Air-Conditioned Private Vehicles in Hong Kong.International journal of environmental research and public health · 2018Article
- Particulate Matter Air Pollution: Effects on the Cardiovascular System.Frontiers in endocrinology · 2018Review
- Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations.Beilstein journal of nanotechnology · 2018Review
- Chemical fractionation and mobility of traffic-related elements in road environments.Environmental geochemistry and health · 2017Article
- Increase in oxidative stress levels following welding fume inhalation: a controlled human exposure study.Particle and fibre toxicology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to fine particulate matter air pollutants (PM2.5) affects heart rate variability parameters, and levels of serum proteins associated with inflammation, hemostasis and thrombosis. This study investigated sources potentially responsible for cardiovascular and hematological effects in highway patrol troopers.
resultsNine healthy young non-smoking male troopers working from 3 PM to midnight were studied on four consecutive days during their shift and the following night. Sources of in-vehicle PM2.5 were identified with variance-maximizing rotational principal factor analysis of PM2.5-components and associated pollutants. Two source models were calculated. Sources of in-vehicle PM2.5 identified were 1) crustal material, 2) wear of steel automotive components, 3) gasoline combustion, 4) speed-changing traffic with engine emissions and brake wear. In one model, sources 1 and 2 collapsed to a single source. Source factors scores were compared to cardiac and blood parameters measured ten and fifteen hours, respectively, after each shift. The "speed-change" factor was significantly associated with mean heart cycle length (MCL, +7% per standard deviation increase in the factor score), heart rate variability (+16%), supraventricular ectopic beats (+39%), % neutrophils (+7%), % lymphocytes (-10%), red blood cell volume MCV (+1%), von Willebrand Factor (+9%), blood urea nitrogen (+7%), and protein C (-11%). The "crustal" factor (but not the "collapsed" source) was associated with MCL (+3%) and serum uric acid concentrations (+5%). Controlling for potential confounders had little influence on the effect estimates.
conclusionPM2.5 originating from speed-changing traffic modulates the autonomic control of the heart rhythm, increases the frequency of premature supraventricular beats and elicits pro-inflammatory and pro-thrombotic responses in healthy young men.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.