ArticleBritish journal of cancer2005
Meat consumption and K-ras mutations in sporadic colon and rectal cancer in The Netherlands Cohort Study.
Article in British journal of cancer, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 6 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 6 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Systematic Analysis of the Differential Effects of Red Meat on Colorectal Cancer Risks: A Meta-Analytic Approach.Journal of gastrointestinal cancer · 2025Pooled it
- Association between red and processed meat consumption and colorectal cancer risk: a comprehensive meta-analysis of prospective studies.GeroScience · 2025Pooled it
- Processed meat intake and incidence of colorectal cancer: a systematic review and meta-analysis of prospective observational studies.European journal of clinical nutrition · 2020Pooled it
- Associations between nutritional factors and KRAS mutations in colorectal cancer: a systematic review.BMC cancer · 2020Pooled it
- Red Meat and Colorectal Cancer: A Quantitative Update on the State of the Epidemiologic Science.Journal of the American College of Nutrition · 2015Pooled it
- Red and processed meat and colorectal cancer incidence: meta-analysis of prospective studies.PloS one · 2011Pooled it
- Unique role of the prospective cohort incident-tumor biobank method in etiological research.Lancet regional health. Americas · 2026Review
- Iron-(Fe3+)-Dependent Reactivation of Telomerase Drives Colorectal Cancers.Cancer discovery · 2024Article
- Review
- Epidemiology, Molecular Mechanisms, and Clinical Trials: an Update on Research on the Association Between Red Meat Consumption and Colorectal Cancer.Current nutrition reports · 2021Review
- Discovery and Features of an Alkylating Signature in Colorectal Cancer.Cancer discovery · 2021Article
- Meat and colorectal cancer in Middle Eastern and North African countries: update of literature review.Public health reviews · 2020Review
- KRAS mutations in the parental tumour accelerate in vitro growth of tumoroids established from colorectal adenocarcinoma.International journal of experimental pathology · 2019Article
- Effects of gene polymorphisms of metabolic enzymes on the association between red and processed meat consumption and the development of colon cancer; a literature review.Journal of nutritional science · 2018Review
- Associations of red and processed meat intake with major molecular pathological features of colorectal cancer.European journal of epidemiology · 2017Article
- Red Meat and Colorectal Cancer.Oncology reviews · 2015Review
- Colorectal cancer: a researcher's perspective of the molecular angel's gone eccentric in the Vale of Kashmir.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013Review
- Article
- Colorectal cancer: molecular mutations and polymorphisms.Frontiers in oncology · 2013Article
- Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Case-cohort analyses were performed on meat and fish consumption in relation to K-ras mutations in 448 colon and 160 rectal cancers that occurred during 7.3 years of follow-up, excluding the first 2.3 years, and 2948 subcohort members of The Netherlands Cohort Study on diet and cancer. Adjusted incidence rate ratios and 95% confidence intervals were computed for colon and rectal cancer and for K-ras mutation status subgroups. Total fresh meat, most types of fresh meat and fish were not associated with colon or rectal cancer, neither overall nor with K-ras mutation status. However, several weak associations were observed for tumours with a wild-type K-ras, including beef and colon tumours, and an inverse association for pork with colon and rectal tumours; for meat products, an increased association was observed with wild-type K-ras tumours in the colon and possibly with G>A transitions in rectal tumours.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.