ArticleRNA (New York, N.Y.)2005
Structural implications of novel diversity in eucaryal RNase P RNA.
Article in RNA (New York, N.Y.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 60 citations in OpenAlex.
- Resurrecting the Activity of the RNA Subunit of Human RNase P.Chembiochem : a European journal of chemical biology · 2026Article
- RNase P: Beyond Precursor tRNA Processing.Genomics, proteomics & bioinformatics · 2024Review
- Piece by piece: Building a ribozyme.The Journal of biological chemistry · 2020Review
- rPredictorDB: a predictive database of individual secondary structures of RNAs and their formatted plots.Database : the journal of biological databases and curation · 2019Article
- The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions.Biomolecules · 2016Review
- Multiple Layers of Stress-Induced Regulation in tRNA Biology.Life (Basel, Switzerland) · 2016Review
- RNase P RNA from the recently evolved plastid of Paulinella and from algae.International journal of molecular sciences · 2014Article
- Vicinal: a method for the determination of ncRNA ends using chimeric reads from RNA-seq experiments.Nucleic acids research · 2014Article
- RNase MRP RNA and RNase P activity in plants are associated with a Pop1p containing complex.Nucleic acids research · 2012Article
- RNase P branches out from RNP to protein: organelle-triggered diversification?Genes & development · 2012Article
- A functional RNase P protein subunit of bacterial origin in some eukaryotes.Molecular genetics and genomics : MGG · 2011Article
- Discovery of a minimal form of RNase P in Pyrobaculum.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex.Nucleic acids research · 2010Article
- Archaeal/eukaryal RNase P: subunits, functions and RNA diversification.Nucleic acids research · 2010Review
- tRNA biology charges to the front.Genes & development · 2010Review
- Bcheck: a wrapper tool for detecting RNase P RNA genes.BMC genomics · 2010Article
- The ancient history of the structure of ribonuclease P and the early origins of Archaea.BMC bioinformatics · 2010Article
- De novo prediction of structured RNAs from genomic sequences.Trends in biotechnology · 2010Review
- High throughput genome-wide survey of small RNAs from the parasitic protists Giardia intestinalis and Trichomonas vaginalis.Genome biology and evolution · 2009Article
- Detection of Balamuthia mandrillaris DNA by real-time PCR targeting the RNase P gene.BMC microbiology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
Previous eucaryotic RNase P RNA secondary structural models have been based on limited diversity, representing only two of the approximately 30 phylogenetic kingdoms of the domain Eucarya. To elucidate a more generally applicable structure, we used biochemical, bioinformatic, and molecular approaches to obtain RNase P RNA sequences from diverse organisms including representatives of six additional kingdoms of eucaryotes. Novel sequences were from acanthamoeba (Acathamoeba castellanii, Balamuthia mandrillaris, Filamoeba nolandi), animals (Caenorhabditis elegans, Drosophila melanogaster), alveolates (Theileria annulata, Babesia bovis), conosids (Dictyostelium discoideum, Physarum polycephalum), trichomonads (Trichomonas vaginalis), microsporidia (Encephalitozoon cuniculi), and diplomonads (Giardia intestinalis). An improved alignment of eucaryal RNase P RNA sequences was assembled and used for statistical and comparative structural analysis. The analysis identifies a conserved core structure of eucaryal RNase P RNA that has been maintained throughout evolution and indicates that covariation in size occurs between some structural elements of the RNA. Eucaryal RNase P RNA contains regions of highly variable length and structure reminiscent of expansion segments found in rRNA. The eucaryal RNA has been remodeled through evolution as a simplified version of the structure found in bacterial and archaeal RNase P RNAs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.