Evidence map›Paper›PMID 15809907›Full record

ArticleThe Journal of infectious diseases2005

Molecular epidemiology of severe acute respiratory syndrome-associated coronavirus infections in Taiwan.

Yu-Ching Lan, Tze-Tze Liu, Jyh-Yuan Yang, Cheng-Ming Lee, Yen-Ju Chen, Yu-Jiun Chan, Jang-Jih Lu, Hsin-Fu Liu, Chao A Hsiung, Mei-Shang Ho and 3 more

Abstract readClinical Conference
In one paragraph

Article in The Journal of infectious diseases, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Phylogenetic perspectives on the epidemiology and origins of SARS and SARS-like coronaviruses.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2009
    Review
  4. Article
  5. Characterizing 56 complete SARS-CoV S-gene sequences from Hong Kong.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2007
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yu-Ching LanAIDS Prevention and Research Centre, National Yang-Ming University, Taiwan, Republic of China.
Tze-Tze Liu
Jyh-Yuan Yang
Cheng-Ming Lee
Yen-Ju Chen
Yu-Jiun Chan
Jang-Jih Lu
Hsin-Fu Liu
Chao A Hsiung
Mei-Shang Ho
Kwang-Jen Hsiao
Hour-Young Chen
Yi-Ming Arthur Chen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2003, Taiwan experienced a series of outbreaks of severe acute respiratory syndrome (SARS) and 1 laboratory-contamination accident. Here we describe a new phylogenetic analytical method to study the sources and dissemination paths of SARS-associated coronavirus (SARS-CoV) infections in Taiwan.

methodsA phylogenetic analytical tool for combining nucleotide sequences from 6 variable regions of a SARS-CoV genome was developed by use of 20 published SARS-CoV sequences; and this method was validated by use of 80 published SARS-CoV sequences. Subsequently, this new tool was applied to provide a better understanding of the entire complement of Taiwanese SARS-CoV isolates, including 20 previously published and 19 identified in this study. The epidemiological data were integrated with the results from the phylogenetic tree and from the nucleotide-signature pattern.

resultsThe topologies of phylogenetic trees generated by the new and the conventional strategies were similar, with the former having better robustness than the latter, especially in comparison with the maximum-likelihood trees: the new strategy revealed that during 2003 there were 5 waves of epidemic SARS-CoV infection, which belonged to 3 phylogenetic clusters in Taiwan.

conclusionsThe new strategy is more efficient than its conventional counterparts. The outbreaks of SARS in Taiwan originated from multiple sources.

Indexed as

Cross InfectionGenome, ViralHumansMolecular EpidemiologyMolecular Sequence DataPhylogenyPolymorphism, Single NucleotideProbabilitySeasonsSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusTaiwanTravel

Identifiers

PMID15809907
PMCPMC7199491

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.