ArticleProceedings of the National Academy of Sciences of the United States of America2005
Parallelism of amino acid changes at the RH1 affecting spectral sensitivity among deep-water cichlids from Lakes Tanganyika and Malawi.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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56 citing papers in PubMed.
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- Visual pigment chromophore usage in Nicaraguan Midas cichlids: phenotypic plasticity and genetic assimilation ofHydrobiologia · 2025Article
- Short-wavelength-sensitive 1 (Ecology and evolution · 2024Article
- Convergent genomic signatures associated with vertebrate viviparity.BMC biology · 2024Article
- Adaptive Evolution of Nearctic Deepwater Fish Vision: Implications for Assessing Functional Variation for Conservation.Molecular biology and evolution · 2024Article
- Discovering genotype-phenotype relationships with machine learning and the Visual Physiology Opsin Database (VPOD).GigaScience · 2024Article
- Multiple axes of visual system diversity in Ithomiini, an ecologically diverse tribe of mimetic butterflies.The Journal of experimental biology · 2023Article
- Genomic Signatures Associated with Transitions to Viviparity in Cyprinodontiformes.Molecular biology and evolution · 2023Article
- Nematostella vectensis exemplifies the exceptional expansion and diversity of opsins in the eyeless Hexacorallia.EvoDevo · 2023Article
- East African cichlid fishes.EvoDevo · 2023Review
- Genetic divergences and hybridization within thePeerJ · 2023Article
- Developmental changes of opsin gene expression in ray-finned fishes (Actinopterygii).Proceedings. Biological sciences · 2022Article
- Neuroanatomical shifts mirror patterns of ecological divergence in three diverse clades of mimetic butterflies.Evolution; international journal of organic evolution · 2022Article
- Contribution of opsins and chromophores to cone pigment variation across populations of Lake Victoria cichlids.Journal of fish biology · 2022Article
- Phylogenomics of trophically diverse cichlids disentangles processes driving adaptive radiation and repeated trophic transitions.Ecology and evolution · 2022Article
- Molecular evolution and depth-related adaptations of rhodopsin in the adaptive radiation of cichlid fishes in Lake Tanganyika.Molecular ecology · 2022Article
- Visual Gene Expression Reveals a cone-to-rod Developmental Progression in Deep-Sea Fishes.Molecular biology and evolution · 2021Article
- A novel terpene synthase controls differences in anti-aphrodisiac pheromone production between closely related Heliconius butterflies.PLoS biology · 2021Article
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8 authors.
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Abstract
Many examples of the appearance of similar traits in different lineages are known during the evolution of organisms. However, the underlying genetic mechanisms have been elucidated in very few cases. Here, we provide a clear example of evolutionary parallelism, involving changes in the same genetic pathway, providing functional adaptation of RH1 pigments to deep-water habitats during the adaptive radiation of East African cichlid fishes. We determined the RH1 sequences from 233 individual cichlids. The reconstruction of cichlid RH1 pigments with 11-cis-retinal from 28 sequences showed that the absorption spectra of the pigments of nine species were shifted toward blue, tuned by two particular amino acid replacements. These blue-shifted RH1 pigments might have evolved as adaptations to the deep-water photic environment. Phylogenetic evidence indicates that one of the replacements, A292S, has evolved several times independently, inducing similar functional change. The parallel evolution of the same mutation at the same amino acid position suggests that the number of genetic changes underlying the appearance of similar traits in cichlid diversification may be fewer than previously expected.
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