Evidence map›Paper›PMID 15809176›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2005

EPR imaging: the relationship between CW spectra acquired from an extended sample subjected to fixed stepped gradients and the Radon transform of the resonance density.

Benjamin B Williams, Xiaochuan Pan, Howard J Halpern

Open access · greenAbstract read
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

  1. Computationally efficient 4D spectral-spatial EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. How in vivo EPR measures and images oxygen.Advances in experimental medicine and biology · 2014
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. EPR oximetry in three spatial dimensions using sparse spin distribution.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2008
    Article
  12. Article
  13. Simulation of 4D spectral-spatial EPR images.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2007
    Article
  14. A parametric approach to spectral-spatial EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2007
    Article
  15. Object dependent sweep width reduction with spectral-spatial EPR imaging.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Benjamin B WilliamsDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA.
Xiaochuan Pan
Howard J Halpern
University of Chicago · US

Funding

Very Low Frequency EPR Imaging in Vivo Phisiology P41 EB02034P41EB002034 · NIBIB · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 2003 to 2017
$16.1M
VERY LOW FREQUENCY EPR IMAGING FOR IN VIVO PHYSIOLOGYP41RR012257 · NCRR · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 1999 to 2002
$2.8M
NCRR NIH HHS P41-RR12257NIBIB NIH HHS P41 EB002034NIBIB NIH HHS P41-EB002034
6 · The paper itself

Abstract

EPR spectroscopy can be extended to a spectroscopic imaging modality by applying magnetic field gradients across the sample to encode spatial information in the measured spectra. In this work, we present a mathematical model of the EPR imaging process in terms of the Radon transform. We describe a model for electron paramagnetic resonance imaging, derive its explicit relationship to the Radon transform, and discuss several options for reconstructing the sample absorption and dispersion densities. An important extension to previous descriptions is the incorporation of large amplitude magnetic field modulation, which can be used to improve the signal-to-noise ratio for continuous wave signal acquisition. Magnetic field modulation is shown to cause well understood changes in the shapes of spectra in the reconstructed images, but does not affect the spatial resolution achieved in these images. Since many of the novel image reconstruction strategies and noise filtering algorithms that have been developed for other modalities start from this formalism, this work allows for their direct application to EPR imaging. This promises to lead to further improvements in EPR imaging techniques.

Indexed as

AlgorithmsElectron Spin Resonance SpectroscopyImage Processing, Computer-AssistedRadonRadon

Identifiers

PMID15809176
PMCPMC12117978
OpenAlexW2089231246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.