ArticleClinical and experimental immunology2005
Circulating YKL-40 levels during human endotoxaemia.
Article in Clinical and experimental immunology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
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Who cites it
22 citing papers in PubMed.
- A randomized prospective cross over study on the effects of medium cut-off membranes on T cellular and serologic immune phenotypes in hemodialysis.Scientific reports · 2022Trial
- Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial.PloS one · 2014Trial
- Inflammatory Effects and Regulatory Mechanisms of Chitinase-3-like-1 in Multiple Human Body Systems: A Comprehensive Review.International journal of molecular sciences · 2024Review
- Early Fever in Allogeneic Stem Cell Transplantation: Are Presepsin and YKL-40 Valuable Diagnostic Tools?Journal of clinical medicine · 2024Article
- Location-based prediction model for Crohn's disease regarding a novel serological marker, anti-chitinase 3-like 1 autoantibodies.World journal of gastroenterology · 2023Article
- Serum YKL-40 as a Potential Biomarker for Sepsis in Term Neonates-A Pilot Study.Children (Basel, Switzerland) · 2023Article
- Environmental stress and nanoplastics' effects onFrontiers in immunology · 2023Article
- Melatonin pretreatment modulates anti-inflammatory, antioxidant, YKL-40, and matrix metalloproteinases in endotoxemic rat lung tissue.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Serum chitotriosidase and YKL-40 in acute pancreatitis: Reliability as prognostic marker for disease severity and correlation with inflammatory markersTurkish journal of medical sciences · 2021Article
- LncRNA KCNQ1OT1 Promotes Proliferation, Invasion and Metastasis of Prostate Cancer by Regulating miR-211-5p/CHI3L1 Pathway.OncoTargets and therapy · 2021Article
- Diet-Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice.Hepatology communications · 2018Article
- Neutrophils as a Potential Source of Chitinase-3-like Protein 1 in Cystic Fibrosis.Inflammation · 2018Article
- Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1β and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia.Infection and immunity · 2016Article
- The Effects of Quercetin on Acute Lung Injury and Biomarkers of Inflammation and Oxidative Stress in the Rat Model of Sepsis.Inflammation · 2016Article
- Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses.Cell host & microbe · 2012Article
- Chitinase-like proteins are candidate biomarkers for sepsis-induced acute kidney injury.Molecular & cellular proteomics : MCP · 2012Article
- YKL-40 expression in CD14⁺ liver cells in acute and chronic injury.World journal of gastroenterology · 2011Article
- Macrophages: master regulators of inflammation and fibrosis.Seminars in liver disease · 2010Review
- YKL-40-A Protein in the Field of Translational Medicine: A Role as a Biomarker in Cancer Patients?Cancers · 2010Article
- High serum YKL-40 level in a cohort of octogenarians is associated with increased risk of all-cause mortality.Clinical and experimental immunology · 2008Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
YKL-40 is secreted by macrophages and neutrophils and patients with bacterial infections have elevated circulating YKL-40. The aim was to evaluate changes in plasma YKL-40 (determined by enzyme-linked immunosorbent assay (ELISA) at 0, 2, 4, 8, 24 and 32 h) in eight healthy volunteers after injection with Esherichia coli endotoxin or saline. Plasma YKL-40 increased after endotoxin injection from 31 microg/l (range 19-39 microg/l) to a maximum of 159 microg/l (61-552 microg/l, P < 0.01) at 24 h. The finding that plasma YKL-40 increased after endotoxin injection compared with saline (P < 0.001) suggests that YKL-40 has a functional role in infections.
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