ArticleGenes & development2005
A novel cell-to-cell trafficking assay indicates that the KNOX homeodomain is necessary and sufficient for intercellular protein and mRNA trafficking.
Article in Genes & development, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 170 citations in OpenAlex.
- The role of phase separation for RNA and protein transport through the nuclear pore complex.Journal of experimental botany · 2026Review
- GHCU, a Molecular Chaperone, Regulates Leaf Curling by Modulating the Distribution of KNGH1 in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Distributing Plant Developmental Regulatory Proteins via Plasmodesmata.Plants (Basel, Switzerland) · 2024Review
- Stem Cells: Engines of Plant Growth and Development.International journal of molecular sciences · 2023Review
- The mRNA mobileome: challenges and opportunities for deciphering signals from the noise.The Plant cell · 2023Review
- Trafficking and localization ofCommunicative & integrative biology · 2022Article
- Plasmodesmata Structural Components and Their Role in Signaling and Plant Development.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Comparative Transcriptome Analysis inFrontiers in genetics · 2021Article
- Identification of BELL Transcription Factors Involved in Nodule Initiation and Development in the LegumesPlants (Basel, Switzerland) · 2020Article
- Functional Validation ofInternational journal of molecular sciences · 2020Article
- Homeoprotein transduction in neurodevelopment and physiopathology.Science advances · 2020Review
- Aiming for the top: non-cell autonomous control of shoot stem cells in Arabidopsis.Journal of plant research · 2020Review
- Genome-scale, single-cell-type resolution of microRNA activities within a whole plant organ.The EMBO journal · 2019Article
- Symplasmic Intercellular Communication through Plasmodesmata.Plants (Basel, Switzerland) · 2018Article
- The Ceratopteris (fern) developing motile gamete walls contain diverse polysaccharides, but not pectin.Planta · 2018Article
- KinG Is a Plant-Specific Kinesin That Regulates Both Intra- and Intercellular Movement of SHORT-ROOT.Plant physiology · 2018Article
- Identification of Plasmodesmal Localization Sequences in Proteins In Planta.Journal of visualized experiments : JoVE · 2017Article
- Lipid Raft, Regulator of Plasmodesmal Callose Homeostasis.Plants (Basel, Switzerland) · 2017Review
- Plasmodesmata-Mediated Cell-to-Cell Communication in the Shoot Apical Meristem: How Stem Cells Talk.Plants (Basel, Switzerland) · 2017Review
- Transcriptomic profiling of taproot growth and sucrose accumulation in sugar beet (Beta vulgaris L.) at different developmental stages.PloS one · 2017Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell-to-cell trafficking of regulatory proteins is a novel mechanism for communication during cell fate specification in plants. Although several developmental proteins traffic cell-to-cell, no signals that are both necessary and sufficient for this function in developmental proteins have been described. We developed a novel trafficking assay using trichome rescue in Arabidopsis. Fusion to KNOTTED1 (KN1) conferred gain-of-trafficking function to the cell-autonomous GLABROUS1 (GL1) protein. We show that the KNOX homeodomain (HD) is necessary and sufficient for intercellular trafficking, identifying a novel function for the HD as the minimal sequence required for trafficking of KN1 and its associated mRNA.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.