ArticleArchaea (Vancouver, B.C.)2002
Getting on target: the archaeal signal recognition particle.
Article in Archaea (Vancouver, B.C.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 59 citations in OpenAlex.
- Archaeal RNA processing and regulation: expanding the functional landscape.Microbiology and molecular biology reviews : MMBR · 2025Review
- The role of SRP9/SRP14 in regulating Alu RNA.RNA biology · 2024Review
- Examining SRP pathway function in mRNA localization to the endoplasmic reticulum.RNA (New York, N.Y.) · 2023Article
- SRPassing Co-translational Targeting: The Role of the Signal Recognition Particle in Protein Targeting and mRNA Protection.International journal of molecular sciences · 2021Review
- Article
- Archaeal cell surface biogenesis.FEMS microbiology reviews · 2018Article
- Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation.Journal of molecular cell biology · 2017Article
- The Archaeal Signal Recognition Particle: Present Understanding and Future Perspective.Current microbiology · 2017Review
- Global mapping transcriptional start sites revealed both transcriptional and post-transcriptional regulation of cold adaptation in the methanogenic archaeon Methanolobus psychrophilus.Scientific reports · 2015Article
- Compositional and structural features related to thermal stability in the archaea SRP19 and SRP54 signal recognition particle proteins.Journal of molecular evolution · 2011Article
- Archaea signal recognition particle shows the way.Archaea (Vancouver, B.C.) · 2010Review
- Compositional properties and thermal adaptation of SRP-RNA in bacteria and archaea.Journal of molecular evolution · 2010Article
- Protein transport across and into cell membranes in bacteria and archaea.Cellular and molecular life sciences : CMLS · 2010Review
- Characterization of the SRP68/72 interface of human signal recognition particle by systematic site-directed mutagenesis.Protein science : a publication of the Protein Society · 2009Article
- Amino acid biases in the N- and C-termini of proteins are evolutionarily conserved and are conserved between functionally related proteins.The protein journal · 2008Article
- The 5e motif of eukaryotic signal recognition particle RNA contains a conserved adenosine for the binding of SRP72.RNA (New York, N.Y.) · 2008Article
- SRP19 is a dispensable component of the signal recognition particle in Archaea.Journal of bacteriology · 2007Article
- The origin and evolution of Archaea: a state of the art.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2006Review
- Protein SRP68 of human signal recognition particle: identification of the RNA and SRP72 binding domains.Protein science : a publication of the Protein Society · 2006Article
- Posttranslational protein modification in Archaea.Microbiology and molecular biology reviews : MMBR · 2005Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Protein translocation begins with the efficient targeting of secreted and membrane proteins to complexes embedded within the membrane. In Eukarya and Bacteria, this is achieved through the interaction of the signal recognition particle (SRP) with the nascent polypeptide chain. In Archaea, homologs of eukaryal and bacterial SRP-mediated translocation pathway components have been identified. Biochemical analysis has revealed that although the archaeal system incorporates various facets of the eukaryal and bacterial targeting systems, numerous aspects of the archaeal system are unique to this domain of life. Moreover, it is becoming increasingly clear that elucidation of the archaeal SRP pathway will provide answers to basic questions about protein targeting that cannot be obtained from examination of eukaryal or bacterial models. In this review, recent data regarding the molecular composition, functional behavior and evolutionary significance of the archaeal signal recognition particle pathway are discussed.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.