Evidence map›Paper›PMID 15796128›Full record

ArticleJournal of autism and developmental disorders2005

Brief report: autistic traits in twins vs. non-twins--a preliminary study.

Alexander Ho, Richard D Todd, John N Constantino

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Spanish Validation of the Autism Spectrum Quotient for Children (AQ-Child-SV).Journal of autism and developmental disorders · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Alcohol dependence in same-sex and opposite-sex twins.Journal of neural transmission (Vienna, Austria : 1996) · 2012
    Article
  15. Validation of proposed DSM-5 criteria for autism spectrum disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2012
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexander HoWashington University School of Medicine, Saint Louis, MO 63110, USA.
Richard D Todd
John N Constantino
Washington University in St. Louis · US

Funding

Autistic Traits: Life Course & Genetic StructureR01HD042541 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2003 to 2012
$4.5M
GENETIC EPIDEMIOLOGY OF ADHDR01MH052813 · NIMH · WASHINGTON UNIVERSITY · PI TODD, RICHARD D · 1996 to 2005
$3.1M
Autism--Development, Genetic Epidemiology and TreatmentR21NS044002 · NINDS · WASHINGTON UNIVERSITY · PI TODD, RICHARD D · 2001 to 2001
$154k
NICHD NIH HHS HD042541NIMH NIH HHS MH52813NINDS NIH HHS NS44002
6 · The paper itself

Abstract

Previous studies have suggested that among affected sib pairs with autism there is an increase in the frequency of twins over what would be expected in comparison to the prevalence of twins in the general population. In this study we sought to determine whether sub-threshold autistic traits were more pronounced in twins than in non-twins. The Social Responsiveness Scale (SRS) was administered in an epidemiologic twin sample (n=802) and in a separate population-based sample of non-twins ascertained from a local school district (n=255). For males (but not females), the mean SRS score was significantly higher among twins than among non-twins. As has been suggested for autism, twin status may incur increased liability to subthreshold autistic symptomatology, particularly in males.

Indexed as

AdolescentAutistic DisorderChildChild, PreschoolCross-Sectional StudiesDiseases in TwinsFemaleHumansMalePersonality InventoryPsychometricsRegistriesRiskSex FactorsStatistics as Topic

Identifiers

PMID15796128
OpenAlexW2005910248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.