Evidence map›Paper›PMID 1579443›Full record

ArticleNucleic acids research1992

C-ski cDNAs are encoded by eight exons, six of which are closely linked within the chicken genome.

H L Grimes, B E Szente, M M Goodenow

Open access · bronzeAbstract read
In one paragraph

Article in Nucleic acids research, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 22 citations in OpenAlex.

  1. Blood · 2018
    Article
  2. Article
  3. Molecular analysis of highly enriched populations of T-cell-depleted monocytes.Clinical and diagnostic laboratory immunology · 1995
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

H L GrimesGraduate Program in Immunology and Molecular Pathology, J.Hillis Miller Health Center, University of Florida, Gainesville 32610.
B E Szente
M M Goodenow
University of Florida Health Science Center · US

Funding

TRAINING IN THE CELL BIOLOGY AND IMMUNOBIOLOGY OF CANCERT32CA009126 · NCI · UNIVERSITY OF FLORIDA · PI MAY, WILLIAM STRATFORD · 1985 to 2012
$3.5M
NCI NIH HHS T32 CA09126
6 · The paper itself

Abstract

The c-ski locus extends a minimum of 65 kb in the chicken genome and is expressed as multiple mRNAs resulting from alternative exon usage. Four exons comprising approximately 1.5 kb of cDNA sequence have been mapped within the chicken c-ski locus. However, c-ski cDNAs include almost 3 kb of sequence for which the exon structure was not defined. From our studies using the polymerase chain reaction and templates of RNA and genomic DNA, it is clear that c-ski cDNAs are encoded by a minimum of eight exons. A long 3' untranslated region is contiguous in the genome with the distal portion of the ski open reading frame such that exon 8 is composed of both coding and noncoding sequences. Exons 2 and 3 are separated by more than 25 kb of genomic sequence. In contrast, exons 3 through 8, representing more than half the length of c-ski cDNA sequences, are closely linked within 10 kb in the chicken genome.

Indexed as

AnimalsBase SequenceBlotting, SouthernChickensDNA-Binding ProteinsExonsIntronsMolecular Sequence DataPolymerase Chain ReactionProto-Oncogene ProteinsProto-OncogenesRNA SplicingDNA-Binding ProteinsProto-Oncogene Proteins

Identifiers

PMID1579443
PMCPMC312231
OpenAlexW1988931978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.