Evidence map›Paper›PMID 15793854›Full record

ReviewWorld journal of gastroenterology2005

Molecular physiology of vesicular glutamate transporters in the digestive system.

Tao Li, Fayez-K Ghishan, Liqun Bai

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Sigma receptors [σRs]: biology in normal and diseased states.Journal of receptor and signal transduction research · 2016
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tao LiDepartments of Pediatrics, Room 3325, Steele Memorial Children's Research Center, University of Arizona Health Sciences Center, Tucson, AZ 85724, USA.
Fayez-K Ghishan
Liqun Bai
Memorial Medical Center · US

Funding

INTESTINAL TRANSPORT OF CALCIUM AND PHOSPHATIDYLINOSITOLR01DK033209 · NIDDK · VANDERBILT UNIVERSITY · PI GHISHAN, FAYEZ KHALAF · 1986 to 2007
$1.8M
Regulation of Digestive Vesicular Glutamate TransporterR01DK063142 · NIDDK · UNIVERSITY OF ARIZONA · PI BAI, LIQUN · 2003 to 2007
$1.2M
NIDDK NIH HHS R01 DK033209NIDDK NIH HHS R01 DK063142NIDDK NIH HHS R01-DK063142NIDDK NIH HHS R01-DK33209
6 · The paper itself

Abstract

Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS). Packaging and storage of glutamate into glutamatergic neuronal vesicles require ATP-dependent vesicular glutamate uptake systems, which utilize the electrochemical proton gradient as a driving force. Three vesicular glutamate transporters (VGLUT1-3) have been recently identified from neuronal tissue where they play a key role to maintain the vesicular glutamate level. Recently, it has been demonstrated that glutamate signaling is also functional in peripheral neuronal and non-neuronal tissues, and occurs in sites of pituitary, adrenal, pineal glands, bone, GI tract, pancreas, skin, and testis. The glutamate receptors and VGLUTs in digestive system have been found in both neuronal and endocrinal cells. The glutamate signaling in the digestive system may have significant relevance to diabetes and GI tract motility disorders. This review will focus on the most recent update of molecular physiology of digestive VGLUTs.

Indexed as

Amino Acid Transport Systems, AcidicAnimalsDigestive SystemHumansMembrane Transport ProteinsProtein Structure, SecondaryVesicular Glutamate Transport Protein 1Vesicular Glutamate Transport Protein 2Vesicular Glutamate Transport ProteinsAmino Acid Transport Systems, AcidicMembrane Transport ProteinsSLC17A6 protein, humanSLC17A7 protein, humanSLC17A8 protein, humanVesicular Glutamate Transport Protein 1Vesicular Glutamate Transport Protein 2Vesicular Glutamate Transport Proteins

Identifiers

PMID15793854
PMCPMC4305864
OpenAlexW2039236037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.