Evidence map›Paper›PMID 15793111›Full record

ArticleAntimicrobial agents and chemotherapy2005

Successive emergence of Enterobacter aerogenes strains resistant to imipenem and colistin in a patient.

Aurélie Thiolas, Claude Bollet, Bernard La Scola, Didier Raoult, Jean-Marie Pagès

Abstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Molecular insights into the evolutionary trajectory of aAntimicrobial agents and chemotherapy · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Antimicrobial Resistance in ESKAPE Pathogens.Clinical microbiology reviews · 2020
    Review
  8. Review
  9. Article
  10. Clinical microbiology reviews · 2019
    Review
  11. Article
  12. Article
  13. Journal of clinical and diagnostic research : JCDR · 2016
    Article
  14. Review
  15. Article
  16. Genome Sequencing of Four Multidrug-ResistantFrontiers in microbiology · 2016
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aurélie ThiolasEnveloppe Bactérienne, Perméabilité et Antibiotiques, EA2197, IFR48, Faculté de Médecine, 27 Blvd. Jean Moulin, 13385 Marseille Cedex 05, France.
Claude Bollet
Bernard La Scola
Didier Raoult
Jean-Marie Pagès

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterobacter aerogenes is an agent of hospital-acquired infection that exhibits a remarkable resistance to beta-lactam antibiotics during therapy. Five successive isolates of E. aerogenes infecting a patient and exhibiting a multiresistance phenotype to beta-lactam antibiotics and fluoroquinolones were investigated. Among these clinical strains, four presented resistant phenotypes during successive imipenem and colistin treatments. The involved resistance mechanisms exhibited by the successive isolates were associated with alterations of the outer membrane that caused a porin decrease and lipopolysaccharide modifications.

Indexed as

Drug Resistance, Multiple, BacterialEvolution, MolecularAnti-Bacterial AgentsColistinDrug Therapy, CombinationEnterobacter aerogenesEnterobacteriaceae InfectionsFemaleHumansImipenemMicrobial Sensitivity TestsMiddle AgedPorinsAnti-Bacterial AgentsColistinImipenemPorins

Identifiers

PMID15793111
PMCPMC1068582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.