ArticleBiophysical journal2005
Coupling field theory with continuum mechanics: a simulation of domain formation in giant unilamellar vesicles.
Article in Biophysical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Modeling membrane reshaping driven by dynamic protein assemblies.Current opinion in structural biology · 2023Review
- Nonaxisymmetric Shapes of Biological Membranes from Locally Induced Curvature.Biophysical journal · 2020Article
- Biophysics of membrane curvature remodeling at molecular and mesoscopic lengthscales.Journal of physics. Condensed matter : an Institute of Physics journal · 2018Article
- The mesoscopic membrane with proteins (MesM-P) model.The Journal of chemical physics · 2017Article
- Multiscale simulations of protein-facilitated membrane remodeling.Journal of structural biology · 2016Review
- Ca-mediated electroformation of cell-sized lipid vesicles.Scientific reports · 2015Article
- Membrane-elasticity model of Coatless vesicle budding induced by ESCRT complexes.PLoS computational biology · 2012Article
- Reconstructing protein remodeled membranes in molecular detail from mesoscopic models.Physical chemistry chemical physics : PCCP · 2011Article
- Multiscale simulation of protein mediated membrane remodeling.Seminars in cell & developmental biology · 2010Review
- Hierarchical coarse-graining strategy for protein-membrane systems to access mesoscopic scales.Faraday discussions · 2010Article
- New insights into BAR domain-induced membrane remodeling.Biophysical journal · 2009Article
- Phase-field modeling of the dynamics of multicomponent vesicles: Spinodal decomposition, coarsening, budding, and fission.Physical review. E, Statistical, nonlinear, and soft matter physics · 2009Article
- Multiscale simulations of heterogeneous model membranes.Biochimica et biophysica acta · 2009Review
- The molecular face of lipid rafts in model membranes.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Verification, validation and sensitivity studies in computational biomechanics.Computer methods in biomechanics and biomedical engineering · 2007Review
- Membrane remodeling from N-BAR domain interactions: insights from multi-scale simulation.Biophysical journal · 2007Article
- Growth dynamics of domains in ternary fluid vesicles.Biophysical journal · 2007Article
- Mesoscopic modeling of bacterial flagellar microhydrodynamics.Biophysical journal · 2006Article
- Closed-loop miscibility gap and quantitative tie-lines in ternary membranes containing diphytanoyl PC.Biophysical journal · 2006Article
- Phase behavior of lipid monolayers containing DPPC and cholesterol analogs.Biophysical journal · 2006Article
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Authors and funding
4 authors.
Funding
Abstract
Domain formation is modeled on the surface of giant unilamellar vesicles using a Landau field theory model for phase coexistence coupled to elastic deformation mechanics (e.g., membrane curvature). Smooth particle applied mechanics, a form of smoothed particle continuum mechanics, is used to solve either the time-dependent Landau-Ginzburg or Cahn-Hilliard free-energy models for the composition dynamics. At the same time, the underlying elastic membrane is modeled using smooth particle applied mechanics, resulting in a unified computational scheme capable of treating the response of the composition fields to arbitrary deformations of the vesicle and vice versa. The results indicate that curvature coupling, along with the field theory model for composition free energy, gives domain formations that are correlated with surface defects on the vesicle. In the case that external deformations are included, the domain structures are seen to respond to such deformations. The present simulation capability provides a significant step forward toward the simulation of realistic cellular membrane processes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.