Evidence map›Paper›PMID 15780145›Full record

Trial reportHealth and quality of life outcomes2005

Health-state valuations for pertussis: methods for valuing short-term health states.

Grace M Lee, Joshua A Salomon, Charles W LeBaron, Tracy A Lieu

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Health and quality of life outcomes, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
14.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. The impact of acute pneumococcal disease on health state utility values: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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  11. Cost-effectiveness of measles control during elimination in Ontario, Canada, 2015.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Grace M LeeCenter for Child Health Care Studies, Department of Ambulatory Care and Prevention, Harvard Pilgrim Health Care and Harvard Medical School, 133 Brookline Ave, 6th floor, Boston, MA 02215, USA. grace_lee@hphc.org
Joshua A Salomon
Charles W LeBaron
Tracy A Lieu
Harvard University · USHarvard Pilgrim Health Care · USNational Center for Immunization and Respiratory Diseases · US

Funding

THE GLOBAL BURDEN OF DISEASE 2000 IN AGING POPULATIONSP01AG017625 · NIA · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI MURRAY, CHRISTOPHER J.L. · 2000 to 2004
$9.4M
Training in Child Health Services Research and Implementation ScienceT32HS000063 · AHRQ · CHILDREN'S HOSPITAL BOSTON · PI GARABEDIAN, LAURA FADEN, WALSH, KATHLEEN ELIZABETH · 1994 to 2024
$7.6M
Strategies for Group A Streptococcal PreventionK08HS013908 · AHRQ · HARVARD PILGRIM HEALTH CARE, INC. · PI LEE, GRACE M · 2004 to 2008
$387k
AHRQ HHS K08 HS013908-01A1AHRQ HHS T32 HS00063NIA NIH HHS P01 AG17625
6 · The paper itself

Abstract

backgroundThe incidence of reported adolescent and adult pertussis continues to rise in the United States. Acellular pertussis vaccines for adolescents and adults have been developed and may be available soon for use in the U.S. Our objectives were: (1) to describe patient valuations of pertussis disease and vaccination; and (2) to compare valuations for short-term and long-term health states associated with pertussis.

methodsWe conducted telephone surveys with 515 adult patients and parents of adolescent patients with pertussis in Massachusetts to determine valuations of pertussis-related health states for disease and vaccination using time trade-off (TTO) and contingent valuation (CV) techniques. Respondents were randomized to complete either a short-term or long-term TTO exercise. Discrimination between health states for each valuation technique was assessed using Tukey's method, and valuations for short-term vs. long-term health states were compared using the Wilcoxon rank-sum test.

resultsThree hundred three (59%) and 309 (60%) respondents completed and understood the TTO and CV exercises, respectively. Overall, respondents gave lower valuations (lower TTO and higher CV values) to avoid a given state for adolescent/adult disease compared to vaccine adverse events. Infant complications due to pertussis were considered worse than adolescent/adult disease, regardless of the method of valuation. The short-term TTO resulted in lower mean valuations and larger mean differences between health states than the long-term TTO exercise.

conclusionPertussis was considered worse than adverse events due to vaccination. Short-term health-state valuation is better able to discriminate among health states, which is useful for cost-utility analysis.

Indexed as

Attitude to HealthQuality of LifeSickness Impact ProfileAcute DiseaseAdolescentAdultAgedAged, 80 and overChoice BehaviorChronic DiseaseDiphtheria-Tetanus-acellular Pertussis VaccinesFemaleHumansMaleMassachusettsMiddle AgedDiphtheria-Tetanus-acellular Pertussis Vaccines

Identifiers

PMID15780145
PMCPMC555848
OpenAlexW2118705380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.