ArticleJournal of dairy science2005
Presence of multidrug-resistant enteric bacteria in dairy farm topsoil.
Article in Journal of dairy science, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 65 citations in OpenAlex.
- Design and evaluation of a streamlined enrichment method for faster co-detection of enteric bacterial pathogens in natural soils and environmental samples.medRxiv : the preprint server for health sciences · 2026Article
- The microbiota vault initiative: safeguarding Earth's microbial heritage for future generations.Nature communications · 2025Review
- Bactericidal activities and biochemical features of 16 antimicrobial peptides against bovine-mastitis causative pathogens.Veterinary research · 2024Article
- Prevalence, Virulence, and Antibiotics Gene Profiles inMicroorganisms · 2023Article
- The spread and antimicrobial resistance of Staphylococcus aureus in South African dairy herds - A review.The Onderstepoort journal of veterinary research · 2021Review
- Monitoring and Characteristics of Major Mastitis Pathogens from Bulk Tank Milk in Korea.Animals : an open access journal from MDPI · 2020Article
- Dairy farm soil presents distinct microbiota and varied prevalence of antibiotic resistance across housing areas.Environmental pollution (Barking, Essex : 1987) · 2019Article
- Multidrug-Resistant Bovine Salmonellosis Predisposing for Severe Human Clostridial Myonecrosis.The American journal of case reports · 2019Article
- Proactive udder health management in South Africa and monitoring of antibiotic resistance of Staphylococcus aureus; in dairy herds from 2001 to 2010.Journal of the South African Veterinary Association · 2018Article
- Control of the pollution of antibiotic resistance genes in soils by quorum sensing inhibition.Environmental science and pollution research international · 2017Article
- Characterization of Four Multidrug Resistance Plasmids Captured from the Sediments of an Urban Coastal Wetland.Frontiers in microbiology · 2017Article
- Environmental and Public Health Implications of Water Reuse: Antibiotics, Antibiotic Resistant Bacteria, and Antibiotic Resistance Genes.Antibiotics (Basel, Switzerland) · 2013Review
- Dairy farm age and resistance to antimicrobial agents in Escherichia coli isolated from dairy topsoil.Current microbiology · 2011Article
- Causes of infection after earthquake, China, 2008.Emerging infectious diseases · 2010Article
- Pasteurized whole milk confers reduced susceptibilities to the antimicrobial agents trimethoprim, gatifloxacin, cefotaxime and tetracycline via the marRAB locus in Escherichia coli.The Journal of dairy research · 2008Article
- Distribution of tetracycline and streptomycin resistance genes and class 1 integrons in Enterobacteriaceae isolated from dairy and nondairy farm soils.Microbial ecology · 2008Article
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3 authors at 1 institution in 1 country.
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Abstract
In addition to human and veterinary medicine, antibiotics are extensively used in agricultural settings, such as for treatment of infections, growth enhancement, and prophylaxis in food animals, leading to selection of drug and multidrug-resistant bacteria. To help circumvent the problem of bacterial antibiotic resistance, it is first necessary to understand the scope of the problem. However, it is not fully understood how widespread antibiotic-resistant bacteria are in agricultural settings. The lack of such surveillance data is especially evident in dairy farm environments, such as soil. It is also unknown to what extent various physiological modulators, such as salicylate, a component of aspirin and known model modulator of multiple antibiotic resistance (mar) genes, influence bacterial multi-drug resistance. We isolated and identified enteric soil bacteria from local dairy farms within Roosevelt County, NM, determined the resistance profiles to antibiotics associated with mar, such as chloramphenicol, nalidixic acid, penicillin G, and tetracycline. We then purified and characterized plasmid DNA and detected mar phenotypic activity. The minimal inhibitory concentrations (MIC) of antibiotics for the isolates ranged from 6 to >50 microg/mL for chloramphenicol, 2 to 8 microg/mL for nalidixic acid, 25 to >300 microg/mL for penicillin G, and 1 to >80 microg/mL for tetracycline. On the other hand, many of the isolates had significantly enhanced MIC for the same antibiotics in the presence of 5 mM salicylate. Plasmid DNA extracted from 12 randomly chosen isolates ranged in size from 6 to 12.5 kb and, in several cases, conferred resistance to chloramphenicol and penicillin G. It is concluded that enteric bacteria from dairy farm topsoil are multidrug resistant and harbor antibiotic-resistance plasmids. A role for dairy topsoil in zoonoses is suggested, implicating this environment as a reservoir for development of bacterial resistance against clinically relevant antibiotics.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.