Evidence map›Paper›PMID 15776219›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2005

Prevalence of vitamin D insufficiency in postmenopausal south Indian women.

C V Harinarayan

Abstract read
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In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 175 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects of a combined alendronate and calcitriol agent (Maxmarvil) on bone metabolism in Korean postmenopausal women: a multicenter, double-blind, randomized, placebo-controlled study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2006
    Trial
  4. Article
  5. Review
  6. Iron and 25-hydroxyvitamin D in postmenopausal women with osteoporosis.American journal of translational research · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Prevalence of hypovitaminosis D in India & way forward.The Indian journal of medical research · 2018
    Review
  15. Article
  16. Article
  17. Vitamin D and acute myocardial infarction.World journal of cardiology · 2017
    Review
  18. Article
  19. Vitamin D Status and Cardio-Metabolic Risk in Indian Postmenopausal Women.Journal of clinical and diagnostic research : JCDR · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

C V HarinarayanDepartment of Endocrinology and Metabolism, Sri Venkateswara Institute of Medical Sciences, 517 507 AP, Tirupati, India. cvharinarayan@yahoo.co.in
Sri Venkateswara Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the dietary calcium and vitamin D status in south Indian postmenopausal women.

methodsPostmenopausal women (n = 164) were evaluated for their daily dietary calcium intake, phytate to calcium ratio, and bone mineral parameters. Their serum leutinizing hormone (LH), follicle-stimulating hormone (FSH), 25-hydroxyvitamin D (25[OH]D), and parathyroid hormone levels (PTH) were measured.

resultsTheir age and BMI were 59.5 +/- 8 years and 27 +/- 5 kg/m2, respectively. Their daily dietary intake of calcium was 323 +/- 66 mg/day; phytate to calcium ratio, 0.56+/-0.1; LH, 26 +/- 13.5 microIU/l; and FSH, 62.6 +/- 30 microIU/l. Their dietary intake of calcium was low compared with the recommended daily/dietary allowance (RDA) of the Indian Council of Medical Research (ICMR) for the Indian population. Of the 164 patients studied, based on population-based reference values, 126 (77%) had normal 25(OH)D levels (9-37.6 ng/ml), and 38 (23%) had 25(OH)D deficiency. Using functional health-based reference values, 30 (18%) patients had normal 25(OH)D levels (> 20 ng/ml), 85 (52%) had 25(OH)D insufficiency (10-20 ng/ml), and 49(30%) had 25(OH)D deficiency (< 10 ng/ml). PTH and serum alkaline phosphatase (SAP) was significantly high in patients with 25(OH)D deficiency (p < 0.05) compared with those with normal 25(OH)D levels. There was a negative correlation between 25(OH)D and PTH (r = -0.2; p < 0.007) and SAP (r = -0.2; p < 0.001). Dietary calcium correlated positively with dietary phosphates (r = 0.8; p < 0.001) and phytate to calcium ratio (r = 0.75; p < 0.001).

conclusionsPopulation-based reference values underdiagnosed vitamin D insufficiency and overdiagnosed normal vitamin D status. The diet was insufficient in calcium and high in phytate. About 82% of the study group had varying degrees of low 25-hydroxyvitamin D levels. The quality of diet has to be improved with enrichment/supplementation of calcium and vitamin D to suppress secondary hyperparathyroidism-induced bone loss and risk of fractures.

Indexed as

PostmenopauseAgedCalcium, DietaryFemaleFollicle Stimulating HormoneHumansIndiaLuteinizing HormoneMiddle AgedParathyroid HormonePrevalenceReference ValuesVitamin DVitamin D Deficiency25-hydroxyvitamin DCalcium, DietaryFollicle Stimulating HormoneLuteinizing HormoneParathyroid HormoneVitamin D

Identifiers

PMID15776219
OpenAlexW2014231301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.